Optimark and Constipation - a phase IV clinical study of FDA data

Summary:

Constipation is reported as a side effect among people who take Optimark (gadoversetamide), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Magnevist, and have Nuclear magnetic resonance imaging brain.

The phase IV clinical study analyzes which people have Constipation when taking Optimark. It is created by eHealthMe based on reports of 3,054 people who have side effects when taking Optimark from the FDA, and is updated regularly.

What is Optimark?

Optimark has active ingredients of gadoversetamide. eHealthMe is studying from 3,055 Optimark users. Check the latest studies of Optimark.

What is Constipation?

Constipation is found to be associated with 3,004 drugs and 4,576 conditions by eHealthMe. Check the latest studies of Constipation.

On Oct, 19, 2025

3,054 people reported to have side effects when taking Optimark.
Among them, 32 people (1.05%) have Constipation.

Among these 32 people:

How long have people been on Optimark when they have Constipation? *

What is the gender of people who have Constipation when taking Optimark? *

female: 58.62 %
male: 41.38 %

What is the age of people who have Constipation when taking Optimark? *

What are other drugs people take besides Optimark? *

Magnevist: 20 people, 62.50%
Omniscan: 14 people, 43.75%
Hydrochlorothiazide: 11 people, 34.38%
Sulfamethoxazole And Trimethoprim: 11 people, 34.38%
Zithromax: 9 people, 28.12%
Alprazolam: 9 people, 28.12%
Metronidazole: 9 people, 28.12%
Lasix: 8 people, 25.00%
Prednisone: 7 people, 21.88%
Acetaminophen And Hydrocodone Bitartrate: 7 people, 21.88%

What are other side effects people have besides Constipation? *

Nephrogenic Systemic Fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease): 29 people, 90.62%
Stress And Anxiety: 17 people, 53.12%
Fall: 17 people, 53.12%
Depression: 17 people, 53.12%
Insomnia (sleeplessness): 16 people, 50.00%
Cardiac Failure Congestive: 15 people, 46.88%
Dizziness: 14 people, 43.75%
Muscle Spasms (muscle contraction): 13 people, 40.62%
Gait Disturbance: 12 people, 37.50%
Night Sweats (sweating in night): 10 people, 31.25%

What are the existing conditions these people have? *

Nuclear Magnetic Resonance Imaging Brain: 7 people, 21.88%
High Blood Pressure: 6 people, 18.75%
Cardiac Disorder: 4 people, 12.50%
Pain: 4 people, 12.50%
Diabetes: 3 people, 9.38%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 3 people, 9.38%
Depression: 3 people, 9.38%
Sleep Disorder: 2 people, 6.25%
Angiopathy (generic term for a disease of the blood vessels): 2 people, 6.25%
Arterial Disorder: 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Optimark and have Constipation?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Optimark:

Optimark (3,055 reports)

Constipation treatments and more:

Constipation (337,856 reports)

Browse all side effects of Optimark:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Constipation:

Constipation (3,004 drugs)

Browse all the conditions that are associated with Constipation:

Constipation (4,576 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on gadoversetamide (the active ingredients of Optimark) and Optimark (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.