Optimark and Ddd - a phase IV clinical study of FDA data

Summary:

Ddd is reported as a side effect among people who take Optimark (gadoversetamide), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Omniscan, and have Nuclear magnetic resonance imaging brain.

The phase IV clinical study analyzes which people have Ddd when taking Optimark. It is created by eHealthMe based on reports of 3,054 people who have side effects when taking Optimark from the FDA, and is updated regularly.

What is Optimark?

Optimark has active ingredients of gadoversetamide. eHealthMe is studying from 3,055 Optimark users. Check the latest studies of Optimark.

What is Ddd?

Ddd is found to be associated with 1,349 drugs and 1,417 conditions by eHealthMe. Check the latest studies of Ddd.



On Jun, 21, 2026

3,054 people reported to have side effects when taking Optimark.
Among them, 15 people (0.49%) have Ddd.

Could Optimark cause Ddd?

Among these 15 people:

How long have people been on Optimark when they have Ddd? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Ddd when taking Optimark? *

  • female: 15.38 %
  • male: 84.62 %

What is the age of people who have Ddd when taking Optimark? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 100 %
  • 60+: 0.0 %

What are other drugs people take besides Optimark? *

  1. Omniscan: 13 people, 86.67%
  2. Magnevist: 5 people, 33.33%
  3. Vancomycin: 4 people, 26.67%
  4. Reglan: 4 people, 26.67%
  5. Phoslo: 4 people, 26.67%
  6. Oxycontin: 4 people, 26.67%
  7. Nexium: 4 people, 26.67%
  8. Coumadin: 4 people, 26.67%
  9. Prohance: 3 people, 20.00%
  10. Multihance: 3 people, 20.00%

What are other side effects people have besides Ddd? *

  1. Nephrogenic Systemic Fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease): 15 people, 100.00%
  2. Confusional State: 12 people, 80.00%
  3. Anaemia (lack of blood): 11 people, 73.33%
  4. Upper Respiratory Tract Infection: 11 people, 73.33%
  5. Pulmonary Hypertension (increase in blood pressure in the lung artery): 11 people, 73.33%
  6. Pneumonia: 11 people, 73.33%
  7. Fluid Overload (too much fluid in the blood): 9 people, 60.00%
  8. Restless Leg Syndrome (a powerful urge to move your legs): 9 people, 60.00%
  9. Intervertebral Disc Protrusion (spinal disc protrusion): 9 people, 60.00%
  10. Staphylococcal Sepsis (blood infection by an infection with staphylococcus bacteria): 9 people, 60.00%

What are the existing conditions these people have? *

  1. Nuclear Magnetic Resonance Imaging Brain: 15 people, 100.00%
  2. Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 4 people, 26.67%
  3. Impaired Gastric Emptying: 4 people, 26.67%
  4. Gastritis (inflammation of stomach): 4 people, 26.67%
  5. Diabetes: 4 people, 26.67%
  6. Bacterial Infection: 4 people, 26.67%
  7. Joint Pain: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Optimark and have Ddd?

- Check whether Ddd is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Optimark:

Ddd treatments and more:

  • Ddd (19,910 reports)

How severe was Ddd and when was it recovered:

Expand to all the drugs that have ingredients of gadoversetamide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Optimark:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ddd:

  • Ddd (1,349 drugs)

Browse all the conditions that are associated with Ddd:

  • Ddd (1,417 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on gadoversetamide (the active ingredients of Optimark) and Optimark (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: