Oracea and Itching - a phase IV clinical study of FDA data

Summary:

Itching is reported as a side effect among people who take Oracea (doxycycline), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Mirvaso, and have High blood pressure.

The phase IV clinical study analyzes which people have Itching when taking Oracea. It is created by eHealthMe based on reports of 1,061 people who have side effects when taking Oracea from the FDA, and is updated regularly.

What is Oracea?

Oracea has active ingredients of doxycycline. It is often used in rosacea. eHealthMe is studying from 1,272 Oracea users. Check the latest studies of Oracea.

What is Itching?

Itching is found to be associated with 3,210 drugs and 4,535 conditions by eHealthMe. Check the latest studies of Itching.

On Jul, 19, 2026

1,061 people reported to have side effects when taking Oracea.
Among them, 38 people (3.58%) have Itching.

Among these 38 people:

How long have people been on Oracea when they have Itching? *

What is the gender of people who have Itching when taking Oracea? *

female: 86.84 %
male: 13.16 %

What is the age of people who have Itching when taking Oracea? *

What are other drugs people take besides Oracea? *

What are other side effects people have besides Itching? *

Rashes (redness): 18 people, 47.37%
Dry Skin: 9 people, 23.68%
Skin Burning Sensation: 7 people, 18.42%
Urticaria (rash of round, red welts on the skin that itch intensely): 5 people, 13.16%
Rash Papular (redness with papule): 4 people, 10.53%
Skin Tightness: 4 people, 10.53%
Drug Ineffective: 4 people, 10.53%
Rash Erythematous (redness of the skin): 4 people, 10.53%
Skin Blushing/flushing (a sudden reddening of the face, neck): 4 people, 10.53%
Swelling Face: 3 people, 7.89%

What are the existing conditions these people have? *

High Blood Pressure: 4 people, 10.53%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 7.89%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 7.89%
High Blood Cholesterol: 3 people, 7.89%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 5.26%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 5.26%
Drowsiness: 2 people, 5.26%
Stress And Anxiety: 2 people, 5.26%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 5.26%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 2.63%

* Approximation only. Some reports may have incomplete information.

Do you take Oracea and have Itching?

- Check whether Itching is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oracea:

Oracea (1,272 reports)

Itching treatments and more:

Itching (398,821 reports)

Browse all side effects of Oracea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Itching:

Itching (3,210 drugs)

Browse all the conditions that are associated with Itching:

Itching (4,535 conditions)

Related publications that referenced our studies

Dmour HH, Zayadeen AR, Shawagfeh JS, "Effect of Long Term Prophylaxis of Antimalarial Drug (Doxycycline) on Liver Span by Ultrasound", Middle East Journal of Internal Medicine, 2013 Jan .
Dmour HH, Zayadeen AR, Shawagfeh JS, "Effect of Long Term Prophylaxis of Antimalarial Drug (Doxycycline) on Liver Span by Ultrasound", Middle East Journal of Internal Medicine, 2013 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on doxycycline (the active ingredients of Oracea) and Oracea (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.