Orap and Fever - a phase IV clinical study of FDA data

Summary:

Fever is reported as a side effect among people who take Orap (pimozide), especially for people who are male, 50-59 old, also take Ribavirin, and have Schizophrenia.

The phase IV clinical study analyzes which people have Fever when taking Orap. It is created by eHealthMe based on reports of 507 people who have side effects when taking Orap from the FDA, and is updated regularly.

What is Orap?

Orap has active ingredients of pimozide. It is often used in gilles de la tourette syndrome. eHealthMe is studying from 544 Orap users. Check the latest studies of Orap.

What is Fever?

Fever is found to be associated with 3,495 drugs and 6,198 conditions by eHealthMe. Check the latest studies of Fever.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Jul, 25, 2026

507 people reported to have side effects when taking Orap.
Among them, 16 people (3.16%) have Fever.

Could Orap cause Fever?

Among these 16 people:

What is the gender of people who have Fever when taking Orap? *

  • female: 33.33 %
  • male: 66.67 %

What is the age of people who have Fever when taking Orap? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 13.33 %
  • 40-49: 6.67 %
  • 50-59: 66.67 %
  • 60+: 13.33 %

What are other drugs people take besides Orap? *

  1. Phenergan: 3 people, 18.75%
  2. Zantac: 3 people, 18.75%
  3. Intron A: 3 people, 18.75%
  4. Ribavirin: 3 people, 18.75%
  5. Coumadin: 2 people, 12.50%
  6. Albendazole: 2 people, 12.50%
  7. Spiriva: 2 people, 12.50%
  8. Risperdal: 2 people, 12.50%
  9. Folic Acid: 2 people, 12.50%
  10. Inderal La: 1 person, 6.25%

What are other side effects people have besides Fever? *

  1. Malaise (a feeling of general discomfort or uneasiness): 4 people, 25.00%
  2. Cardiac Arrest: 4 people, 25.00%
  3. Hypotension (abnormally low blood pressure): 4 people, 25.00%
  4. Diarrhea: 3 people, 18.75%
  5. Intestinal Ischaemia (decreased supply of oxygenated blood to the intestines): 3 people, 18.75%
  6. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 3 people, 18.75%
  7. Sinus Tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 3 people, 18.75%
  8. Insomnia (sleeplessness): 3 people, 18.75%
  9. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 3 people, 18.75%
  10. Pneumonia Streptococcal (pneumonia, caused by streptococcus pneumoniae): 3 people, 18.75%

What are the existing conditions these people have? *

  1. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 3 people, 18.75%
  2. Reflux Gastritis (a condition in which the lining of a person's stomach becomes inflamed as a result of exposure to bile): 2 people, 12.50%
  3. Pinworms: 2 people, 12.50%
  4. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 2 people, 12.50%
  5. Schizoaffective Disorder (a mental disorder characterized by disordered thought): 1 person, 6.25%
  6. Nervous System Disorder (a general class of medical conditions affecting the nervous system): 1 person, 6.25%
  7. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 6.25%
  8. Multiple Myeloma (cancer of the plasma cells): 1 person, 6.25%
  9. Insomnia (sleeplessness): 1 person, 6.25%
  10. Apnea (temporary absence or cessation of breathing): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Orap and have Fever?

- Check whether Fever is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Orap:

  • Orap (544 reports)

Fever treatments and more:

  • Fever (498,666 reports)

How severe was Fever and when was it recovered:

Expand to all the drugs that have ingredients of pimozide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Orap:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fever:

Browse all the conditions that are associated with Fever:

  • Fever (6,198 conditions)

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on pimozide (the active ingredients of Orap) and Orap (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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