Orapred and Bradycardia - a phase IV clinical study of FDA data

Summary:

Bradycardia is reported as a side effect among people who take Orapred (prednisolone sodium phosphate), especially for people who are male, 0-1 old, also take Vitamin D3, and have Spinal muscular atrophy.

The phase IV clinical study analyzes which people have Bradycardia when taking Orapred. It is created by eHealthMe based on reports of 393 people who have side effects when taking Orapred from the FDA, and is updated regularly.

What is Orapred?

Orapred has active ingredients of prednisolone sodium phosphate. It is often used in croup. eHealthMe is studying from 428 Orapred users. Check the latest studies of Orapred.

What is Bradycardia?

Bradycardia (abnormally slow heart action) is found to be associated with 1,917 drugs and 3,119 conditions by eHealthMe. Check the latest studies of Bradycardia.

On Aug, 11, 2026

393 people reported to have side effects when taking Orapred.
Among them, 14 people (3.56%) have Bradycardia.

Among these 14 people:

What is the gender of people who have Bradycardia when taking Orapred? *

female: 28.57 %
male: 71.43 %

What is the age of people who have Bradycardia when taking Orapred? *

What are other drugs people take besides Orapred? *

What are other side effects people have besides Bradycardia? *

Acute Hepatic Failure: 10 people, 71.43%
Laryngospasm (an uncontrolled/involuntary muscular contraction of larynx): 10 people, 71.43%
Jaundice - Yellow Skin (a yellowish pigmentation of the skin): 7 people, 50.00%
Liver Injury: 7 people, 50.00%
Aspartate Aminotransferase Increased: 6 people, 42.86%
Hypotension (abnormally low blood pressure): 2 people, 14.29%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 2 people, 14.29%
Autoimmune Hepatitis: 2 people, 14.29%
Glycosuria (excretion of glucose into the urine): 1 person, 7.14%
Feeding Tube Complication: 1 person, 7.14%

What are the existing conditions these people have? *

Spinal Muscular Atrophy (wasting of spinal muscles): 12 people, 85.71%
Constipation: 2 people, 14.29%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 7.14%
Sleep Disorder: 1 person, 7.14%
Pain: 1 person, 7.14%
Nausea (feeling of having an urge to vomit): 1 person, 7.14%
Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 1 person, 7.14%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.14%
Cough: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Orapred and have Bradycardia?

- Check whether Bradycardia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Orapred:

Orapred (428 reports)

Bradycardia treatments and more:

Bradycardia (61,180 reports)

Browse all side effects of Orapred:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bradycardia:

Bradycardia (1,917 drugs)

Browse all the conditions that are associated with Bradycardia:

Bradycardia (3,119 conditions)

Related publications that referenced our studies

Schlumbrecht MP, Hehr K, "Cisplatin-induced bradycardia and the importance of the QT interval", Journal of Oncology Pharmacy Practice, 2015 Jan .
Oflaz MB, Kucukdurmaz Z, Guven AS, Karapinar H, Kaya A, Sancakdar E, Deveci K, Gul I, Erdem A, Cevit O, Icagasioglu FD, "Bradycardia seen in children with Crimean-Congo hemorrhagic fever", Vector-Borne and Zoonotic Diseases, 2013 Nov .
Schlumbrecht MP, Hehr K, "Cisplatin-induced bradycardia and the importance of the QT interval", Journal of Oncology Pharmacy Practice, 2015 Jan .
Oflaz MB, Kucukdurmaz Z, Guven AS, Karapinar H, Kaya A, Sancakdar E, Deveci K, Gul I, Erdem A, Cevit O, Icagasioglu FD, "Bradycardia seen in children with Crimean-Congo hemorrhagic fever", Vector-Borne and Zoonotic Diseases, 2013 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on prednisolone sodium phosphate (the active ingredients of Orapred) and Orapred (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.