Orencia and Bone erosion - a phase IV clinical study of FDA data

Summary:

Bone erosion is reported as a side effect among people who take Orencia (abatacept), especially for people who are female, 50-59 old, have been taking the drug for 1 - 2 years also take Enbrel, and have Pain.

The phase IV clinical study analyzes which people have Bone erosion when taking Orencia. It is created by eHealthMe based on reports of 135,080 people who have side effects when taking Orencia from the FDA, and is updated regularly.

What is Orencia?

Orencia has active ingredients of abatacept. It is often used in rheumatoid arthritis. eHealthMe is studying from 135,415 Orencia users. Check the latest studies of Orencia.

What is Bone erosion?

Bone erosion is found to be associated with 495 drugs and 297 conditions by eHealthMe. Check the latest studies of Bone erosion.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

135,080 people reported to have side effects when taking Orencia.
Among them, 1,593 people (1.18%) have Bone erosion.

Among these 1,593 people:

* Approximation only. Some reports may have incomplete information.

Do you take Orencia and have Bone erosion?

- Check whether Bone erosion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Orencia:

Orencia (135,415 reports)

Bone erosion treatments and more:

Bone erosion (4,590 reports)

How severe was Bone erosion and when was it recovered:

Bone erosion in Orencia

Expand to all the drugs that have ingredients of abatacept:

Bone erosion and drugs with ingredients of abatacept (1,647 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Orencia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bone erosion:

Bone erosion (495 drugs)

Browse all the conditions that are associated with Bone erosion:

Bone erosion (297 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on abatacept (the active ingredients of Orencia) and Orencia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.