Orgovyx and Thin bones - a phase IV clinical study of FDA data

Summary:

Thin bones is reported as a side effect among people who take Orgovyx (relugolix), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Prednisone, and have Prostate cancer.

The phase IV clinical study analyzes which people have Thin bones when taking Orgovyx. It is created by eHealthMe based on reports of 7,213 people who have side effects when taking Orgovyx from the FDA, and is updated regularly.

What is Orgovyx?

Orgovyx has active ingredients of relugolix. eHealthMe is studying from 7,216 Orgovyx users. Check the latest studies of Orgovyx.

What is Thin bones?

Thin bones is found to be associated with 2,546 drugs and 1,908 conditions by eHealthMe. Check the latest studies of Thin bones.



On Nov, 12, 2025

7,213 people reported to have side effects when taking Orgovyx.
Among them, 10 people (0.14%) have Thin bones.

Could Orgovyx cause Thin bones?

Among these 10 people:

How long have people been on Orgovyx when they have Thin bones? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Thin bones when taking Orgovyx? *

  • female: 0.0 %
  • male: 100 %

What is the age of people who have Thin bones when taking Orgovyx? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

What are other drugs people take besides Orgovyx? *

  1. Zytiga: 2 people, 20.00%
  2. Vitamin B12: 2 people, 20.00%
  3. Prednisone: 2 people, 20.00%
  4. Xgeva: 1 person, 10.00%
  5. Prevacid: 1 person, 10.00%
  6. Mometasone Furoate: 1 person, 10.00%
  7. Hydrocodone: 1 person, 10.00%
  8. Humira: 1 person, 10.00%
  9. Enzalutamide: 1 person, 10.00%

What are other side effects people have besides Thin bones? *

  1. Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 4 people, 40.00%
  2. Diarrhea: 3 people, 30.00%
  3. Dizziness: 3 people, 30.00%
  4. Weakness: 2 people, 20.00%
  5. Loose Tooth: 2 people, 20.00%
  6. Constipation: 2 people, 20.00%
  7. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 2 people, 20.00%
  8. Fatigue (feeling of tiredness): 2 people, 20.00%
  9. Gynecomastia (enlargement of the gland tissue of the male breast): 2 people, 20.00%
  10. Urticaria (rash of round, red welts on the skin that itch intensely): 2 people, 20.00%

What are the existing conditions these people have? *

  1. Prostate Cancer: 10 people, 100.00%
  2. Pernicious Anaemia (anaemia due to lack of vitamin b12): 1 person, 10.00%
  3. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 10.00%
  4. Anaemia (lack of blood): 1 person, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Orgovyx and have Thin bones?

- Check whether Thin bones is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Orgovyx:

Thin bones treatments and more:

How severe was Thin bones and when was it recovered:

Expand to all the drugs that have ingredients of relugolix:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Orgovyx:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Thin bones:

Browse all the conditions that are associated with Thin bones:


How the study uses the data?

The study uses data from the FDA. It is based on relugolix (the active ingredients of Orgovyx) and Orgovyx (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: