Orilissa and Hypophagia - a phase IV clinical study of FDA data

Summary:

Hypophagia is reported as a side effect among people who take Orilissa (elagolix sodium), especially for people who are female, 20-29 old, and have Endometriosis.

The phase IV clinical study analyzes which people have Hypophagia when taking Orilissa. It is created by eHealthMe based on reports of 3,300 people who have side effects when taking Orilissa from the FDA, and is updated regularly.

What is Orilissa?

Orilissa has active ingredients of elagolix sodium. eHealthMe is studying from 3,314 Orilissa users. Check the latest studies of Orilissa.

What is Hypophagia?

Hypophagia (reduced food intake) is found to be associated with 1,486 drugs and 1,395 conditions by eHealthMe. Check the latest studies of Hypophagia.



On Jul, 20, 2026

3,300 people reported to have side effects when taking Orilissa.
Among them, 11 people (0.33%) have Hypophagia.

Could Orilissa cause Hypophagia?

Among these 11 people:

What is the gender of people who have Hypophagia when taking Orilissa? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Hypophagia when taking Orilissa? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 40 %
  • 30-39: 20 %
  • 40-49: 20 %
  • 50-59: 20 %
  • 60+: 0.0 %

What are other side effects people have besides Hypophagia? *

  1. Nausea (feeling of having an urge to vomit): 4 people, 36.36%
  2. Diarrhea: 3 people, 27.27%
  3. Weight Decreased: 3 people, 27.27%
  4. Pain: 3 people, 27.27%
  5. Nausea And Vomiting: 3 people, 27.27%
  6. Weight Increased: 2 people, 18.18%
  7. Abdominal Pain: 2 people, 18.18%
  8. Back Pain: 2 people, 18.18%
  9. Fatigue (feeling of tiredness): 2 people, 18.18%
  10. Feeling Abnormal: 2 people, 18.18%

What are the existing conditions these people have? *

  1. Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain): 7 people, 63.64%
  2. Abdominal Pain: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Orilissa and have Hypophagia?

- Check whether Hypophagia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Orilissa:

Hypophagia treatments and more:

How severe was Hypophagia and when was it recovered:

Expand to all the drugs that have ingredients of elagolix sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Orilissa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypophagia:

Browse all the conditions that are associated with Hypophagia:


How the study uses the data?

The study uses data from the FDA. It is based on elagolix sodium (the active ingredients of Orilissa) and Orilissa (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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