Ornithine and Insomnia - a phase IV clinical study of FDA data

Summary:

Insomnia is reported as a side effect among people who take Ornithine (ornithine), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Neurontin, and have The flu.

The phase IV clinical study analyzes which people have Insomnia when taking Ornithine. It is created by eHealthMe based on reports of 581 people who have side effects when taking Ornithine from the FDA, and is updated regularly.

What is Ornithine?

Ornithine has active ingredients of ornithine. eHealthMe is studying from 591 Ornithine users. Check the latest studies of Ornithine.

What is Insomnia?

Insomnia (sleeplessness) is found to be associated with 3,115 drugs and 5,173 conditions by eHealthMe. Check the latest studies of Insomnia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 14, 2026

581 people reported to have side effects when taking Ornithine.
Among them, 19 people (3.27%) have Insomnia.

Could Ornithine cause Insomnia?

Among these 19 people:

How long have people been on Ornithine when they have Insomnia? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Insomnia when taking Ornithine? *

  • female: 88.89 %
  • male: 11.11 %

What is the age of people who have Insomnia when taking Ornithine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 77.78 %
  • 50-59: 0.0 %
  • 60+: 22.22 %

What are other drugs people take besides Ornithine? *

  1. Acetaminophen: 15 people, 78.95%
  2. Trazodone Hydrochloride: 15 people, 78.95%
  3. Alprazolam: 15 people, 78.95%
  4. Dronabinol: 15 people, 78.95%
  5. Emend: 15 people, 78.95%
  6. Euthyrox: 15 people, 78.95%
  7. Hydromorphone Hydrochloride: 15 people, 78.95%
  8. Valacyclovir Hydrochloride: 15 people, 78.95%
  9. Neulasta: 15 people, 78.95%
  10. Neurontin: 15 people, 78.95%

What are other side effects people have besides Insomnia? *

  1. Weakness: 17 people, 89.47%
  2. Iron Deficiency Anaemia: 15 people, 78.95%
  3. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 15 people, 78.95%
  4. Blood Bilirubin Increased: 15 people, 78.95%
  5. Canker Sores (painful, open sore in the mouth): 15 people, 78.95%
  6. Diarrhea: 15 people, 78.95%
  7. Gamma-Glutamyltransferase Increased: 15 people, 78.95%
  8. Intracranial Pressure Increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid): 15 people, 78.95%
  9. General Physical Health Deterioration (weak health status): 15 people, 78.95%
  10. Thrombocytopenia (decrease of platelets in blood): 15 people, 78.95%

What are the existing conditions these people have? *

  1. The Flu (the flu is caused by an influenza virus): 14 people, 73.68%
  2. Gamma-Glutamyltransferase Increased: 13 people, 68.42%
  3. Diarrhea: 13 people, 68.42%
  4. Intracranial Pressure Increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid): 2 people, 10.53%
  5. Pain: 1 person, 5.26%
  6. Multiple Myeloma (cancer of the plasma cells): 1 person, 5.26%
  7. Iron Deficiency Anaemia: 1 person, 5.26%
  8. Immunodeficiency Disorders: 1 person, 5.26%
  9. Babesiosis (malaria-like parasitic disease caused by infection with babesia): 1 person, 5.26%
  10. Ammonia Abnormal: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Ornithine and have Insomnia?

- Check whether Insomnia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ornithine:

Insomnia treatments and more:

How severe was Insomnia and when was it recovered:

Expand to all the drugs that have ingredients of ornithine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ornithine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Insomnia:

Browse all the conditions that are associated with Insomnia:


How the study uses the data?

The study uses data from the FDA. It is based on ornithine (the active ingredients of Ornithine) and Ornithine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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