Ortho tri-cyclen and Ectopic pregnancy - a phase IV clinical study of FDA data

Summary:

Ectopic pregnancy is reported as a side effect among people who take Ortho tri-cyclen (ethinyl estradiol; norgestimate), especially for people who are 20-29 old, also take Mirena, and have Depression.

The phase IV clinical study analyzes which people have Ectopic pregnancy when taking Ortho tri-cyclen. It is created by eHealthMe based on reports of 4,840 people who have side effects when taking Ortho tri-cyclen from the FDA, and is updated regularly.

What is Ortho tri-cyclen?

Ortho tri-cyclen has active ingredients of ethinyl estradiol; norgestimate. It is often used in birth control. eHealthMe is studying from 5,699 Ortho tri-cyclen users. Check the latest studies of Ortho tri-cyclen.

What is Ectopic pregnancy?

Ectopic pregnancy (a pregnancy in which the foetus develops outside the uterus, typically in a fallopian tube) is found to be associated with 200 drugs and 617 conditions by eHealthMe. Check the latest studies of Ectopic pregnancy.

On Jul, 14, 2026

4,840 people reported to have side effects when taking Ortho tri-cyclen.
Among them, 16 people (0.33%) have Ectopic pregnancy.

Could Ortho tri-cyclen cause Ectopic pregnancy?

Among these 16 people:

What is the age of people who have Ectopic pregnancy when taking Ortho tri-cyclen? *

What are other drugs people take besides Ortho tri-cyclen? *

What are other side effects people have besides Ectopic pregnancy? *

Vaginal Infection: 2 people, 12.50%
Pregnancy On Oral Contraceptive: 2 people, 12.50%
Drug Exposure During Pregnancy: 2 people, 12.50%
Hair Loss: 2 people, 12.50%
Hot Flush (sudden feelings of heat): 2 people, 12.50%
Hypertriglyceridaemia (excess of triglycerides in the blood): 1 person, 6.25%
Abortion Induced (medically referred abortion): 1 person, 6.25%
Abortion Spontaneous (naturally occurring miscarriage): 1 person, 6.25%
Amenorrhea (absence of a menstrual period in a woman of reproductive age): 1 person, 6.25%
Bipolar Disorder (mood disorder): 1 person, 6.25%

What are the existing conditions these people have? *

Depression: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Ortho tri-cyclen and have Ectopic pregnancy?

- Check whether Ectopic pregnancy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ortho tri-cyclen:

Ortho tri-cyclen (5,699 reports)

Ectopic pregnancy treatments and more:

Ectopic pregnancy (4,918 reports)

How severe was Ectopic pregnancy and when was it recovered:

Ectopic pregnancy in Ortho tri-cyclen

Expand to all the drugs that have ingredients of ethinyl estradiol; norgestimate:

Ectopic pregnancy and drugs with ingredients of ethinyl estradiol; norgestimate (24 reports)

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ortho tri-cyclen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ectopic pregnancy:

Ectopic pregnancy (200 drugs)

Browse all the conditions that are associated with Ectopic pregnancy:

Ectopic pregnancy (617 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ethinyl estradiol; norgestimate (the active ingredients of Ortho tri-cyclen) and Ortho tri-cyclen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.