Osphena and Arrhythmias - a phase IV clinical study of FDA data

Summary:

Arrhythmias is reported as a side effect among people who take Osphena (ospemifene), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Vitamin B12, and have Neuropathy peripheral.

The phase IV clinical study analyzes which people have Arrhythmias when taking Osphena. It is created by eHealthMe based on reports of 2,741 people who have side effects when taking Osphena from the FDA, and is updated regularly.

What is Osphena?

Osphena has active ingredients of ospemifene. eHealthMe is studying from 2,762 Osphena users. Check the latest studies of Osphena.

What is Arrhythmias?

Arrhythmias (irregular heartbeat) is found to be associated with 2,758 drugs and 4,837 conditions by eHealthMe. Check the latest studies of Arrhythmias.

On May, 05, 2026

2,741 people reported to have side effects when taking Osphena.
Among them, 12 people (0.44%) have Arrhythmias.

Among these 12 people:

How long have people been on Osphena when they have Arrhythmias? *

What is the gender of people who have Arrhythmias when taking Osphena? *

female: 100 %
male: 0.0 %

What is the age of people who have Arrhythmias when taking Osphena? *

What are other drugs people take besides Osphena? *

What are other side effects people have besides Arrhythmias? *

Hepatic Enzyme Increased: 7 people, 58.33%
Nausea (feeling of having an urge to vomit): 5 people, 41.67%
Weight Fluctuation: 4 people, 33.33%
Abdominal Pain Upper: 4 people, 33.33%
Diarrhea: 4 people, 33.33%
Alcoholism (problems with alcohol): 3 people, 25.00%
Canker Sores (painful, open sore in the mouth): 3 people, 25.00%
Eye Inflammation: 3 people, 25.00%
Hypoaesthesia (reduced sense of touch or sensation): 3 people, 25.00%
Muscle Spasms (muscle contraction): 3 people, 25.00%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 25.00%
Neuropathy Peripheral (surface nerve damage): 3 people, 25.00%
Vulvovaginal Dryness: 1 person, 8.33%
Sexual Intercourse - Painful: 1 person, 8.33%
Pain: 1 person, 8.33%
High Blood Pressure: 1 person, 8.33%
Cystitis Interstitial (unknown cause characterized by bladder pain): 1 person, 8.33%
Constipation: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Osphena and have Arrhythmias?

- Check whether Arrhythmias is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Osphena:

Osphena (2,762 reports)

Arrhythmias treatments and more:

Arrhythmias (177,908 reports)

Browse all side effects of Osphena:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Arrhythmias:

Arrhythmias (2,758 drugs)

Browse all the conditions that are associated with Arrhythmias:

Arrhythmias (4,837 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ospemifene (the active ingredients of Osphena) and Osphena (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.