Otezla and Drug intolerance - a phase IV clinical study of FDA data

Summary:

Drug intolerance is reported as a side effect among people who take Otezla (apremilast), especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months also take Humira, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Drug intolerance when taking Otezla. It is created by eHealthMe based on reports of 146,032 people who have side effects when taking Otezla from the FDA, and is updated regularly.

What is Otezla?

Otezla has active ingredients of apremilast. It is often used in psoriatic arthritis. eHealthMe is studying from 146,254 Otezla users. Check the latest studies of Otezla.

What is Drug intolerance?

Drug intolerance (drug sensitivity) is found to be associated with 1,908 drugs and 1,598 conditions by eHealthMe. Check the latest studies of Drug intolerance.

On Jul, 08, 2026

146,032 people reported to have side effects when taking Otezla.
Among them, 2,760 people (1.89%) have Drug intolerance.

Among these 2,760 people:

* Approximation only. Some reports may have incomplete information.

Do you take Otezla and have Drug intolerance?

- Check whether Drug intolerance is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Otezla:

Otezla (146,254 reports)

Drug intolerance treatments and more:

Drug intolerance (103,988 reports)

How severe was Drug intolerance and when was it recovered:

Drug intolerance in Otezla

Expand to all the drugs that have ingredients of apremilast:

Drug intolerance and drugs with ingredients of apremilast

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Otezla:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Drug intolerance:

Drug intolerance (1,908 drugs)

Browse all the conditions that are associated with Drug intolerance:

Drug intolerance (1,598 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on apremilast (the active ingredients of Otezla) and Otezla (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.