Oxbryta and C. diff - a phase IV clinical study of FDA data

Summary:

C. diff is reported only by a few people who take Oxbryta.

The study analyzes which people take Oxbryta and have C. diff. It is created by eHealthMe based on reports of 24,969 people who have side effects while taking Oxbryta from the FDA, and is updated regularly.

What is Oxbryta?

Oxbryta has active ingredients of voxelotor. eHealthMe is studying from 24,969 Oxbryta users. Check the latest studies of Oxbryta.

What is C. diff?

C. diff is found to be associated with 1,578 drugs and 1,776 conditions by eHealthMe. Check the latest studies of C. diff.



On Jun, 18, 2026

24,969 people reported to have side effects when taking Oxbryta.
Among them, 3 people (0.01%) have C. diff.

Could Oxbryta cause C. diff?

Among these 3 people:

What is the gender of people who have C. diff when taking Oxbryta? *

  • female: 33.33 %
  • male: 66.67 %

What is the age of people who have C. diff when taking Oxbryta? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 33.33 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 66.67 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

What are other drugs people take besides Oxbryta? *

  1. Hydroxyurea: 3 people, 100.00%
  2. Sertraline: 2 people, 66.67%
  3. Zofran: 1 person, 33.33%
  4. Vitamin D: 1 person, 33.33%
  5. Tylenol: 1 person, 33.33%
  6. Symbicort: 1 person, 33.33%
  7. Prevacid: 1 person, 33.33%
  8. Penicillin: 1 person, 33.33%
  9. Pamelor: 1 person, 33.33%
  10. Miralax: 1 person, 33.33%

What are other side effects people have besides C. diff? *

  1. Renal Impairment (severely reduced kidney function): 2 people, 66.67%
  2. Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin): 1 person, 33.33%
  3. Rashes (redness): 1 person, 33.33%
  4. Mycobacterial Infection: 1 person, 33.33%
  5. Itching: 1 person, 33.33%
  6. Hypersensitivity: 1 person, 33.33%
  7. Epstein-Barr Virus Infection: 1 person, 33.33%
  8. Chest Pain: 1 person, 33.33%
  9. Arterial Thrombosis (formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system): 1 person, 33.33%

What are the existing conditions these people have? *

  1. Depression: 2 people, 66.67%
  2. Anaemia (lack of blood): 2 people, 66.67%
  3. Pain: 1 person, 33.33%
  4. Nausea And Vomiting: 1 person, 33.33%
  5. Muscle Spasms (muscle contraction): 1 person, 33.33%
  6. Immunodeficiency Common Variable: 1 person, 33.33%
  7. Constipation: 1 person, 33.33%
  8. Burkholderia Cepacia Complex Infection (complex infection by group of bacteria burkholderia cepacia -resistant to common antibiotics): 1 person, 33.33%
  9. Asthma: 1 person, 33.33%

* Approximation only. Some reports may have incomplete information.

Do you take Oxbryta and have C. diff?

- Check whether C. diff is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxbryta:

C. diff treatments and more:

How severe was C. diff and when was it recovered:

Expand to all the drugs that have ingredients of voxelotor:

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oxbryta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with C. diff:

Browse all the conditions that are associated with C. diff:


How the study uses the data?

The study uses data from the FDA. It is based on voxelotor (the active ingredients of Oxbryta) and Oxbryta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: