Oxycodone and acetaminophen and Anorectal abscess - a phase IV clinical study of FDA data

Summary:

Anorectal abscess is reported as a side effect among people who take Oxycodone and acetaminophen (acetaminophen; oxycodone hydrochloride), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Acetaminophen, and have Crohn's disease.

The phase IV clinical study analyzes which people have Anorectal abscess when taking Oxycodone and acetaminophen. It is created by eHealthMe based on reports of 13,404 people who have side effects when taking Oxycodone and acetaminophen from the FDA, and is updated regularly.

What is Oxycodone and acetaminophen?

Oxycodone and acetaminophen has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 14,467 Oxycodone and acetaminophen users. Check the latest studies of Oxycodone and acetaminophen.

What is Anorectal abscess?

Anorectal abscess is found to be associated with 645 drugs and 979 conditions by eHealthMe. Check the latest studies of Anorectal abscess.



On Aug, 06, 2026

13,404 people reported to have side effects when taking Oxycodone and acetaminophen.
Among them, 14 people (0.1%) have Anorectal abscess.

Could Oxycodone and acetaminophen cause Anorectal abscess?

Among these 14 people:

How long have people been on Oxycodone and acetaminophen when they have Anorectal abscess? *

  • < 1 month: 80 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 20 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Anorectal abscess when taking Oxycodone and acetaminophen? *

  • female: 28.57 %
  • male: 71.43 %

What is the age of people who have Anorectal abscess when taking Oxycodone and acetaminophen? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 8.33 %
  • 20-29: 0.0 %
  • 30-39: 25.0 %
  • 40-49: 0.0 %
  • 50-59: 50.0 %
  • 60+: 16.67 %

What are other drugs people take besides Oxycodone and acetaminophen? *

  1. Acetaminophen: 5 people, 35.71%
  2. Vitamin D: 3 people, 21.43%
  3. Oxycodone: 3 people, 21.43%
  4. Ondansetron: 3 people, 21.43%
  5. Novolog: 3 people, 21.43%
  6. Morphine: 3 people, 21.43%
  7. Humira: 3 people, 21.43%
  8. Flagyl: 3 people, 21.43%
  9. Vancomycin: 3 people, 21.43%
  10. Phenergan: 3 people, 21.43%

What are other side effects people have besides Anorectal abscess? *

  1. Haemorrhoids (a swollen vein or group of veins in the region of the anus): 4 people, 28.57%
  2. Cellulitis (infection under the skin): 4 people, 28.57%
  3. Perineal Abscess: 3 people, 21.43%
  4. Groin Abscess (pus in groin): 3 people, 21.43%
  5. Sepsis (a severe blood infection that can lead to organ failure and death): 3 people, 21.43%
  6. Chronic Kidney Disease: 2 people, 14.29%
  7. Leukocytosis (increased white blood cells): 2 people, 14.29%
  8. Fistula (an abnormal connection or passageway between two): 2 people, 14.29%
  9. Aseptic Necrosis (the death of bone tissue due to a lack of blood supply): 2 people, 14.29%
  10. Necrotising Fasciitis (an uncommon life-threatening soft-tissue infection): 2 people, 14.29%

What are the existing conditions these people have? *

  1. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 7 people, 50.00%
  2. Abdominal Pain: 3 people, 21.43%
  3. Procedural Pain: 3 people, 21.43%
  4. Haemostasis (stopping of bleeding): 3 people, 21.43%
  5. Hypotension (abnormally low blood pressure): 2 people, 14.29%
  6. Type 2 Diabetes: 2 people, 14.29%
  7. Nausea And Vomiting: 2 people, 14.29%
  8. Weight Decreased: 2 people, 14.29%
  9. Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 2 people, 14.29%
  10. Rickets (softening of bones): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and acetaminophen and have Anorectal abscess?

- Check whether Anorectal abscess is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycodone and acetaminophen:

Anorectal abscess treatments and more:

How severe was Anorectal abscess and when was it recovered:

Expand to all the drugs that have ingredients of acetaminophen; oxycodone hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oxycodone and acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Anorectal abscess:

Browse all the conditions that are associated with Anorectal abscess:


How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; oxycodone hydrochloride (the active ingredients of Oxycodone and acetaminophen) and Oxycodone and acetaminophen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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