Oxycodone and acetaminophen and Disease progression - a phase IV clinical study of FDA data

Summary:

Disease progression is reported as a side effect among people who take Oxycodone and acetaminophen (acetaminophen; oxycodone hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Ondansetron, and have Nausea.

The phase IV clinical study analyzes which people have Disease progression when taking Oxycodone and acetaminophen. It is created by eHealthMe based on reports of 13,404 people who have side effects when taking Oxycodone and acetaminophen from the FDA, and is updated regularly.

What is Oxycodone and acetaminophen?

Oxycodone and acetaminophen has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 14,467 Oxycodone and acetaminophen users. Check the latest studies of Oxycodone and acetaminophen.

What is Disease progression?

Disease progression is found to be associated with 1,799 drugs and 2,257 conditions by eHealthMe. Check the latest studies of Disease progression.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

13,404 people reported to have side effects when taking Oxycodone and acetaminophen.
Among them, 54 people (0.4%) have Disease progression.

Could Oxycodone and acetaminophen cause Disease progression?

Among these 54 people:

How long have people been on Oxycodone and acetaminophen when they have Disease progression? *

What is the gender of people who have Disease progression when taking Oxycodone and acetaminophen? *

female: 46.81 %
male: 53.19 %

What is the age of people who have Disease progression when taking Oxycodone and acetaminophen? *

What are other drugs people take besides Oxycodone and acetaminophen? *

What are other side effects people have besides Disease progression? *

Weight Decreased: 10 people, 18.52%
Diarrhea: 10 people, 18.52%
Weakness: 9 people, 16.67%
Fatigue (feeling of tiredness): 9 people, 16.67%
Dyspnea (difficult or laboured breathing): 8 people, 14.81%
Joint Pain: 6 people, 11.11%
Anaemia (lack of blood): 6 people, 11.11%
Pain In Extremity: 6 people, 11.11%
Haemoglobin Decreased: 5 people, 9.26%
Dehydration (dryness resulting from the removal of water): 5 people, 9.26%

What are the existing conditions these people have? *

High Blood Pressure: 6 people, 11.11%
Nausea (feeling of having an urge to vomit): 6 people, 11.11%
Colon Cancer: 5 people, 9.26%
Prostate Cancer: 5 people, 9.26%
Diabetes: 4 people, 7.41%
Breast Cancer: 4 people, 7.41%
Constipation: 3 people, 5.56%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 3 people, 5.56%
Nausea And Vomiting: 3 people, 5.56%
Neoplasm Malignant (cancer tumour): 3 people, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and acetaminophen and have Disease progression?

- Check whether Disease progression is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycodone and acetaminophen:

Oxycodone and acetaminophen (14,467 reports)

Disease progression treatments and more:

Disease progression (115,298 reports)

How severe was Disease progression and when was it recovered:

Disease progression in Oxycodone and acetaminophen

Expand to all the drugs that have ingredients of acetaminophen; oxycodone hydrochloride:

Disease progression and drugs with ingredients of acetaminophen; oxycodone hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oxycodone and acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Disease progression:

Disease progression (1,799 drugs)

Browse all the conditions that are associated with Disease progression:

Disease progression (2,257 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; oxycodone hydrochloride (the active ingredients of Oxycodone and acetaminophen) and Oxycodone and acetaminophen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.