Oxycodone and acetaminophen and Vaginal bleeding - a phase IV clinical study of FDA data

Summary:

Vaginal bleeding is reported as a side effect among people who take Oxycodone and acetaminophen (acetaminophen; oxycodone hydrochloride), especially for people who are 60+ old, have been taking the drug for 2 - 5 years also take Xarelto, and have Cataplexy.

The phase IV clinical study analyzes which people have Vaginal bleeding when taking Oxycodone and acetaminophen. It is created by eHealthMe based on reports of 13,404 people who have side effects when taking Oxycodone and acetaminophen from the FDA, and is updated regularly.

What is Oxycodone and acetaminophen?

Oxycodone and acetaminophen has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 14,467 Oxycodone and acetaminophen users. Check the latest studies of Oxycodone and acetaminophen.

What is Vaginal bleeding?

Vaginal bleeding is found to be associated with 1,130 drugs and 1,535 conditions by eHealthMe. Check the latest studies of Vaginal bleeding.



On Jul, 15, 2026

13,404 people reported to have side effects when taking Oxycodone and acetaminophen.
Among them, 15 people (0.11%) have Vaginal bleeding.

Could Oxycodone and acetaminophen cause Vaginal bleeding?

Among these 15 people:

How long have people been on Oxycodone and acetaminophen when they have Vaginal bleeding? *

  • < 1 month: 20 %
  • 1 - 6 months: 20 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 60 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the age of people who have Vaginal bleeding when taking Oxycodone and acetaminophen? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 18.18 %
  • 30-39: 9.09 %
  • 40-49: 0.0 %
  • 50-59: 27.27 %
  • 60+: 45.45 %

What are other drugs people take besides Oxycodone and acetaminophen? *

  1. Proair Hfa: 3 people, 20.00%
  2. Avapro: 3 people, 20.00%
  3. Imdur: 3 people, 20.00%
  4. Nuvigil: 3 people, 20.00%
  5. Tribenzor: 3 people, 20.00%
  6. Exforge Hct: 3 people, 20.00%
  7. Vesicare: 3 people, 20.00%
  8. Sertraline: 3 people, 20.00%
  9. Lisinopril: 3 people, 20.00%
  10. Xarelto: 3 people, 20.00%

What are other side effects people have besides Vaginal bleeding? *

  1. Dyspnea (difficult or laboured breathing): 5 people, 33.33%
  2. Stress And Anxiety: 4 people, 26.67%
  3. Chest Pain: 4 people, 26.67%
  4. Depression: 4 people, 26.67%
  5. Fatigue (feeling of tiredness): 4 people, 26.67%
  6. Fall: 4 people, 26.67%
  7. Drug Hypersensitivity: 4 people, 26.67%
  8. Nausea (feeling of having an urge to vomit): 4 people, 26.67%
  9. Postmenopausal Haemorrhage (post-menopausal bleeding): 3 people, 20.00%
  10. Rotator Cuff Syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder): 3 people, 20.00%

What are the existing conditions these people have? *

  1. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 20.00%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 20.00%
  3. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 20.00%
  4. Birth Control: 2 people, 13.33%
  5. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 13.33%
  6. Ovarian Cancer (cancer of ovary): 1 person, 6.67%
  7. Ovarian Vein Thrombosis (clot formation in ovary vein): 1 person, 6.67%
  8. Pulmonary Embolism (blockage of the main artery of the lung): 1 person, 6.67%
  9. Borderline Personality Disorder: 1 person, 6.67%
  10. Breast Cancer: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and acetaminophen and have Vaginal bleeding?

- Check whether Vaginal bleeding is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycodone and acetaminophen:

Vaginal bleeding treatments and more:

How severe was Vaginal bleeding and when was it recovered:

Expand to all the drugs that have ingredients of acetaminophen; oxycodone hydrochloride:

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oxycodone and acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Vaginal bleeding:

Browse all the conditions that are associated with Vaginal bleeding:


How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; oxycodone hydrochloride (the active ingredients of Oxycodone and acetaminophen) and Oxycodone and acetaminophen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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