Oxycodone hydrochloride and Enlarged heart - a phase IV clinical study of FDA data

Summary:

Enlarged heart is reported as a side effect among people who take Oxycodone hydrochloride (oxycodone hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Prednisone, and have Asthma.

The phase IV clinical study analyzes which people have Enlarged heart when taking Oxycodone hydrochloride. It is created by eHealthMe based on reports of 36,410 people who have side effects when taking Oxycodone hydrochloride from the FDA, and is updated regularly.

What is Oxycodone hydrochloride?

Oxycodone hydrochloride has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 36,817 Oxycodone hydrochloride users. Check the latest studies of Oxycodone hydrochloride.

What is Enlarged heart?

Enlarged heart is found to be associated with 1,456 drugs and 1,663 conditions by eHealthMe. Check the latest studies of Enlarged heart.

On Jul, 12, 2026

36,410 people reported to have side effects when taking Oxycodone hydrochloride.
Among them, 29 people (0.08%) have Enlarged heart.

Could Oxycodone hydrochloride cause Enlarged heart?

Among these 29 people:

How long have people been on Oxycodone hydrochloride when they have Enlarged heart? *

What is the gender of people who have Enlarged heart when taking Oxycodone hydrochloride? *

female: 69.23 %
male: 30.77 %

What is the age of people who have Enlarged heart when taking Oxycodone hydrochloride? *

What are other drugs people take besides Oxycodone hydrochloride? *

What are other side effects people have besides Enlarged heart? *

Dyspnea (difficult or laboured breathing): 11 people, 37.93%
Headache (pain in head): 9 people, 31.03%
Weakness: 8 people, 27.59%
Cardiac Disorder: 8 people, 27.59%
Fever: 8 people, 27.59%
Fatigue (feeling of tiredness): 8 people, 27.59%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 8 people, 27.59%
Pneumonia: 8 people, 27.59%
Nausea (feeling of having an urge to vomit): 7 people, 24.14%
High Blood Pressure: 7 people, 24.14%

What are the existing conditions these people have? *

Asthma: 4 people, 13.79%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 10.34%
Intervertebral Disc Protrusion (spinal disc protrusion): 2 people, 6.90%
Carpal Tunnel Syndrome (nerve compression at wrist results numbness weakness, pain , swelling): 2 people, 6.90%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 6.90%
Overdose: 2 people, 6.90%
Multiple Myeloma (cancer of the plasma cells): 2 people, 6.90%
Migraine (headache): 2 people, 6.90%
Hypersensitivity: 2 people, 6.90%
Hereditary Disorder: 1 person, 3.45%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone hydrochloride and have Enlarged heart?

- Check whether Enlarged heart is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycodone hydrochloride:

Oxycodone hydrochloride (36,817 reports)

Enlarged heart treatments and more:

Enlarged heart (20,022 reports)

Browse all side effects of Oxycodone hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Enlarged heart:

Enlarged heart (1,456 drugs)

Browse all the conditions that are associated with Enlarged heart:

Enlarged heart (1,663 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride (the active ingredients of Oxycodone hydrochloride) and Oxycodone hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.