Oxycodone hydrochloride and Lyme disease - a phase IV clinical study of FDA data

Summary:

Lyme disease is reported as a side effect among people who take Oxycodone hydrochloride (oxycodone hydrochloride), especially for people who are female, 30-39 old, have been taking the drug for 1 - 2 years also take Gabapentin, and have Narcolepsy.

The phase IV clinical study analyzes which people have Lyme disease when taking Oxycodone hydrochloride. It is created by eHealthMe based on reports of 36,410 people who have side effects when taking Oxycodone hydrochloride from the FDA, and is updated regularly.

What is Oxycodone hydrochloride?

Oxycodone hydrochloride has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 36,817 Oxycodone hydrochloride users. Check the latest studies of Oxycodone hydrochloride.

What is Lyme disease?

Lyme disease (a bacterial infection that is spread to humans by infected ticks) is found to be associated with 431 drugs and 620 conditions by eHealthMe. Check the latest studies of Lyme disease.



On Jul, 19, 2026

36,410 people reported to have side effects when taking Oxycodone hydrochloride.
Among them, 20 people (0.05%) have Lyme disease.

Could Oxycodone hydrochloride cause Lyme disease?

Among these 20 people:

How long have people been on Oxycodone hydrochloride when they have Lyme disease? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 100 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Lyme disease when taking Oxycodone hydrochloride? *

  • female: 87.5 %
  • male: 12.5 %

What is the age of people who have Lyme disease when taking Oxycodone hydrochloride? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 37.5 %
  • 30-39: 37.5 %
  • 40-49: 0.0 %
  • 50-59: 12.5 %
  • 60+: 12.5 %

What are other drugs people take besides Oxycodone hydrochloride? *

  1. Gabapentin: 9 people, 45.00%
  2. Breo Ellipta: 8 people, 40.00%
  3. Singulair: 8 people, 40.00%
  4. Lidocaine: 7 people, 35.00%
  5. Epinephrine: 7 people, 35.00%
  6. Vitamin D3: 7 people, 35.00%
  7. Acetaminophen: 7 people, 35.00%
  8. Mirtazapine: 7 people, 35.00%
  9. Xyrem: 6 people, 30.00%
  10. Fentanyl: 6 people, 30.00%

What are other side effects people have besides Lyme disease? *

  1. Weight Decreased: 8 people, 40.00%
  2. High Blood Pressure: 6 people, 30.00%
  3. Joint Pain: 6 people, 30.00%
  4. Headache (pain in head): 6 people, 30.00%
  5. Sialoadenitis (inflammation of a salivary gland): 5 people, 25.00%
  6. Sinus Disorder (disease of sinus): 5 people, 25.00%
  7. Malaise (a feeling of general discomfort or uneasiness): 5 people, 25.00%
  8. Staphylococcal Infection (an infection with staphylococcus bacteria): 5 people, 25.00%
  9. Pneumonia: 5 people, 25.00%
  10. Poor Venous Access: 5 people, 25.00%

What are the existing conditions these people have? *

  1. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 30.00%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 30.00%
  3. Immunodeficiency: 5 people, 25.00%
  4. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 4 people, 20.00%
  5. Neurogenic Bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion): 2 people, 10.00%
  6. Nausea And Vomiting: 2 people, 10.00%
  7. Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function): 2 people, 10.00%
  8. Depression: 2 people, 10.00%
  9. Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer): 2 people, 10.00%
  10. Erosive Oesophagitis (acid reflux disease can cause tissue damage in the oesophagus over time): 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone hydrochloride and have Lyme disease?

- Check whether Lyme disease is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycodone hydrochloride:

Lyme disease treatments and more:

How severe was Lyme disease and when was it recovered:

Expand to all the drugs that have ingredients of oxycodone hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oxycodone hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lyme disease:

Browse all the conditions that are associated with Lyme disease:


How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride (the active ingredients of Oxycodone hydrochloride) and Oxycodone hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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