Oxycodone and Bladder perforation - a phase IV clinical study of FDA data

Summary:

Bladder perforation is reported as a side effect among people who take Oxycodone (oxycodone hydrochloride), especially for people who are male, 60+ old, also take Enzalutamide, and have High blood pressure.

The phase IV clinical study analyzes which people have Bladder perforation when taking Oxycodone. It is created by eHealthMe based on reports of 159,853 people who have side effects when taking Oxycodone from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,592 Oxycodone users. Check the latest studies of Oxycodone.

What is Bladder perforation?

Bladder perforation (bladder trauma) is found to be associated with 56 drugs and 130 conditions by eHealthMe. Check the latest studies of Bladder perforation.

On May, 04, 2026

159,853 people reported to have side effects when taking Oxycodone.
Among them, 7 people (0.0%) have Bladder perforation.

Could Oxycodone cause Bladder perforation?

Among these 7 people:

What is the gender of people who have Bladder perforation when taking Oxycodone? *

female: 40 %
male: 60 %

What is the age of people who have Bladder perforation when taking Oxycodone? *

What are other drugs people take besides Oxycodone? *

What are other side effects people have besides Bladder perforation? *

Pelvic Pain: 3 people, 42.86%
Neuroendocrine Carcinoma (cancer tumour that arise from cells of the endocrine (hormonal) and nervous systems): 2 people, 28.57%
Haematuria (presence of blood in urine): 2 people, 28.57%
Prostate Cancer: 1 person, 14.29%
Procedural Pain: 1 person, 14.29%
Post Procedural Complication: 1 person, 14.29%
Nerve Injury: 1 person, 14.29%
Iatrogenic Injury (iatrogenic injury is a form of medical error): 1 person, 14.29%
Gastrointestinal Perforation (hole in the digestive tract): 1 person, 14.29%
Drug Dependence: 1 person, 14.29%

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 3 people, 42.86%
High Blood Pressure: 3 people, 42.86%
Urinary Tract Infection: 1 person, 14.29%
Transitional Cell Carcinoma (cancer tumour inner most layer of urinary system): 1 person, 14.29%
Transitional Cell Cancer Of The Renal Pelvis And Ureter (a cancer of transitional cell of renal pelvis and ureter): 1 person, 14.29%
Stress And Anxiety: 1 person, 14.29%
Rashes (redness): 1 person, 14.29%
Prostate Cancer Metastatic: 1 person, 14.29%
Indigestion: 1 person, 14.29%
Gastric Disorder (disease of stomach): 1 person, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and have Bladder perforation?

- Check whether Bladder perforation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycodone:

Oxycodone (162,592 reports)

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bladder perforation:

Bladder perforation (56 drugs)

Browse all the conditions that are associated with Bladder perforation:

Bladder perforation (130 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride (the active ingredients of Oxycodone) and Oxycodone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.