Oxycodone and Chronic hepatic failure - a phase IV clinical study of FDA data

Summary:

Chronic hepatic failure is reported as a side effect among people who take Oxycodone (oxycodone hydrochloride), especially for people who are male, 40-49 old, also take Amlodipine, and have High blood pressure.

The phase IV clinical study analyzes which people have Chronic hepatic failure when taking Oxycodone. It is created by eHealthMe based on reports of 159,853 people who have side effects when taking Oxycodone from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,592 Oxycodone users. Check the latest studies of Oxycodone.

What is Chronic hepatic failure?

Chronic hepatic failure (long lasting liver failure) is found to be associated with 104 drugs and 224 conditions by eHealthMe. Check the latest studies of Chronic hepatic failure.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

159,853 people reported to have side effects when taking Oxycodone.
Among them, 19 people (0.01%) have Chronic hepatic failure.

Could Oxycodone cause Chronic hepatic failure?

Among these 19 people:

What is the gender of people who have Chronic hepatic failure when taking Oxycodone? *

female: 36.84 %
male: 63.16 %

What is the age of people who have Chronic hepatic failure when taking Oxycodone? *

What are other drugs people take besides Oxycodone? *

What are other side effects people have besides Chronic hepatic failure? *

Hepatitis C: 6 people, 31.58%
Acute Kidney Failure: 6 people, 31.58%
Hypotension (abnormally low blood pressure): 5 people, 26.32%
Abdominal Pain: 4 people, 21.05%
Hepatic Neoplasm Malignant (liver cancer): 4 people, 21.05%
Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 4 people, 21.05%
Septic Shock (shock due to blood infection): 4 people, 21.05%
Cardiac Arrest: 3 people, 15.79%
Dyspnea (difficult or laboured breathing): 3 people, 15.79%
Diabetes: 3 people, 15.79%

What are the existing conditions these people have? *

High Blood Pressure: 5 people, 26.32%
Hepatitis C: 3 people, 15.79%
Diabetes: 3 people, 15.79%
Chest Pain: 2 people, 10.53%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 10.53%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 10.53%
Portopulmonary Hypertension (coexistence of portal and pulmonary hypertension): 2 people, 10.53%
Gastritis (inflammation of stomach): 2 people, 10.53%
Obstructive Airways Disorder (a progressive disease that makes it hard to breathe): 2 people, 10.53%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and have Chronic hepatic failure?

- Check whether Chronic hepatic failure is associated with a drug or a condition
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- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycodone:

Oxycodone (162,592 reports)

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Chronic hepatic failure:

Chronic hepatic failure (104 drugs)

Browse all the conditions that are associated with Chronic hepatic failure:

Chronic hepatic failure (224 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride (the active ingredients of Oxycodone) and Oxycodone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.