Oxycodone and Coronary artery stenosis - a phase IV clinical study of FDA data

Summary:

Coronary artery stenosis is reported as a side effect among people who take Oxycodone (oxycodone hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Acetaminophen, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Coronary artery stenosis when taking Oxycodone. It is created by eHealthMe based on reports of 159,853 people who have side effects when taking Oxycodone from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,592 Oxycodone users. Check the latest studies of Oxycodone.

What is Coronary artery stenosis?

Coronary artery stenosis (narrowing of coronary artery) is found to be associated with 606 drugs and 829 conditions by eHealthMe. Check the latest studies of Coronary artery stenosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

159,853 people reported to have side effects when taking Oxycodone.
Among them, 58 people (0.04%) have Coronary artery stenosis.

Could Oxycodone cause Coronary artery stenosis?

Among these 58 people:

How long have people been on Oxycodone when they have Coronary artery stenosis? *

What is the gender of people who have Coronary artery stenosis when taking Oxycodone? *

female: 47.27 %
male: 52.73 %

What is the age of people who have Coronary artery stenosis when taking Oxycodone? *

What are other drugs people take besides Oxycodone? *

Acetaminophen: 11 people, 18.97%
Aspirin: 8 people, 13.79%
Diazepam: 7 people, 12.07%
Lisinopril: 7 people, 12.07%
Neurontin: 6 people, 10.34%
Coreg: 6 people, 10.34%
Diphenhydramine Hydrochloride: 6 people, 10.34%
Folic Acid: 6 people, 10.34%
Furosemide: 6 people, 10.34%
Losartan: 6 people, 10.34%

What are other side effects people have besides Coronary artery stenosis? *

Chest Pain: 13 people, 22.41%
Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 11 people, 18.97%
Pneumonia: 11 people, 18.97%
Pulmonary Oedema (fluid accumulation in the lungs): 10 people, 17.24%
Arteriosclerosis Coronary Artery (thickening and hardening of arteries- coronary artery): 9 people, 15.52%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 9 people, 15.52%
Dyspnea (difficult or laboured breathing): 9 people, 15.52%
Heart Attack: 9 people, 15.52%
Cardiac Failure Congestive: 8 people, 13.79%
Malaise (a feeling of general discomfort or uneasiness): 8 people, 13.79%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 6.90%
Primary Myelofibrosis (primary disorder of the bone marrow): 3 people, 5.17%
Stress And Anxiety: 3 people, 5.17%
Sleep Disorder: 3 people, 5.17%
Ischaemic Cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease): 2 people, 3.45%
Cardiac Failure Chronic: 2 people, 3.45%
Cardiac Failure: 2 people, 3.45%
Carcinoid Tumor Of The Gastrointestinal Tract: 2 people, 3.45%
Type 2 Diabetes: 2 people, 3.45%
Irritable Bowel Syndrome: 2 people, 3.45%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and have Coronary artery stenosis?

- Check whether Coronary artery stenosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycodone:

Oxycodone (162,592 reports)

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Coronary artery stenosis:

Coronary artery stenosis (606 drugs)

Browse all the conditions that are associated with Coronary artery stenosis:

Coronary artery stenosis (829 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride (the active ingredients of Oxycodone) and Oxycodone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.