Oxycodone and Dysaesthesia - a phase IV clinical study of FDA data

Summary:

Dysaesthesia is reported as a side effect among people who take Oxycodone (oxycodone hydrochloride), especially for people who are male, 30-39 old, have been taking the drug for 1 - 6 months also take Advil, and have Constipation.

The phase IV clinical study analyzes which people have Dysaesthesia when taking Oxycodone. It is created by eHealthMe based on reports of 159,853 people who have side effects when taking Oxycodone from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,592 Oxycodone users. Check the latest studies of Oxycodone.

What is Dysaesthesia?

Dysaesthesia (abnormal sensation) is found to be associated with 522 drugs and 584 conditions by eHealthMe. Check the latest studies of Dysaesthesia.



On Jun, 09, 2026

159,853 people reported to have side effects when taking Oxycodone.
Among them, 50 people (0.03%) have Dysaesthesia.

Could Oxycodone cause Dysaesthesia?

Among these 50 people:

How long have people been on Oxycodone when they have Dysaesthesia? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Dysaesthesia when taking Oxycodone? *

  • female: 46.94 %
  • male: 53.06 %

What is the age of people who have Dysaesthesia when taking Oxycodone? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 36.59 %
  • 40-49: 17.07 %
  • 50-59: 26.83 %
  • 60+: 19.51 %

What are other drugs people take besides Oxycodone? *

  1. Advil: 16 people, 32.00%
  2. Oxycontin: 15 people, 30.00%
  3. Prozac: 14 people, 28.00%
  4. Paxil: 11 people, 22.00%
  5. Gabapentin: 9 people, 18.00%
  6. Prednisone: 9 people, 18.00%
  7. Klonopin: 9 people, 18.00%
  8. Neurontin: 9 people, 18.00%
  9. Ambien: 9 people, 18.00%
  10. Motrin: 9 people, 18.00%

What are other side effects people have besides Dysaesthesia? *

  1. Headache (pain in head): 22 people, 44.00%
  2. Hypoaesthesia (reduced sense of touch or sensation): 22 people, 44.00%
  3. Nausea (feeling of having an urge to vomit): 20 people, 40.00%
  4. Depression: 20 people, 40.00%
  5. Weakness: 19 people, 38.00%
  6. Fatigue (feeling of tiredness): 17 people, 34.00%
  7. Pain In Extremity: 17 people, 34.00%
  8. Rhinorrhea (watery mucus discharge from the nose): 15 people, 30.00%
  9. Fall: 14 people, 28.00%
  10. Fever: 13 people, 26.00%

What are the existing conditions these people have? *

  1. Constipation: 10 people, 20.00%
  2. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 8 people, 16.00%
  3. Anaemia (lack of blood): 8 people, 16.00%
  4. Rickets (softening of bones): 7 people, 14.00%
  5. Afterbirth Pain: 7 people, 14.00%
  6. Birth Control: 7 people, 14.00%
  7. Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 14.00%
  8. Depression: 6 people, 12.00%
  9. Peripheral Sensory Neuropathy (damage to one or more of your peripheral nerves): 6 people, 12.00%
  10. Multiple Myeloma (cancer of the plasma cells): 5 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and have Dysaesthesia?

- Check whether Dysaesthesia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycodone:

Dysaesthesia treatments and more:

How severe was Dysaesthesia and when was it recovered:

Expand to all the drugs that have ingredients of oxycodone hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Dysaesthesia:

Browse all the conditions that are associated with Dysaesthesia:


How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride (the active ingredients of Oxycodone) and Oxycodone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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