Oxycodone and Dyssomnia - a phase IV clinical study of FDA data

Summary:

Dyssomnia is reported as a side effect among people who take Oxycodone (oxycodone hydrochloride), especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months also take Enbrel, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Dyssomnia when taking Oxycodone. It is created by eHealthMe based on reports of 159,853 people who have side effects when taking Oxycodone from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,583 Oxycodone users. Check the latest studies of Oxycodone.

What is Dyssomnia?

Dyssomnia (sleeping disorders that make it difficult to get to sleep) is found to be associated with 4,715 drugs and 5,212 conditions by eHealthMe. Check the latest studies of Dyssomnia.

On Sep, 21, 2025

159,853 people reported to have side effects when taking Oxycodone.
Among them, 4,903 people (3.07%) have Dyssomnia.

Among these 4,903 people:

How long have people been on Oxycodone when they have Dyssomnia? *

What is the gender of people who have Dyssomnia when taking Oxycodone? *

female: 67.61 %
male: 32.39 %

What is the age of people who have Dyssomnia when taking Oxycodone? *

What are other drugs people take besides Oxycodone? *

What are other side effects people have besides Dyssomnia? *

Fatigue (feeling of tiredness): 2,074 people, 42.30%
Headache (pain in head): 1,793 people, 36.57%
Rashes (redness): 1,699 people, 34.65%
Diarrhea: 1,611 people, 32.86%
Joint Pain: 1,582 people, 32.27%
Weakness: 1,508 people, 30.76%
Joint Swelling: 1,480 people, 30.19%
Nausea (feeling of having an urge to vomit): 1,369 people, 27.92%
Drug Ineffective: 1,352 people, 27.57%
Nausea And Vomiting: 1,351 people, 27.55%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1,605 people, 32.74%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 574 people, 11.71%
Psoriasis (immune-mediated disease that affects the skin): 355 people, 7.24%
Stress And Anxiety: 308 people, 6.28%
Depression: 219 people, 4.47%
High Blood Pressure: 215 people, 4.39%
Multiple Myeloma (cancer of the plasma cells): 184 people, 3.75%
Adenomatous Polyposis Coli ((fap) is an inherited condition in which numerous polyps form mainly in the epithelium of the large intestine): 175 people, 3.57%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 174 people, 3.55%
Fibromyalgia (a long-term condition which causes pain all over the body): 165 people, 3.37%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and have Dyssomnia?

- Check whether Dyssomnia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycodone:

Oxycodone (162,583 reports)

Dyssomnia treatments and more:

Dyssomnia (437,959 reports)

Common Oxycodone side effects:

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Dyssomnia:

Browse all the drugs that are associated with Dyssomnia:

Dyssomnia (4,715 drugs)

Common conditions associated with Dyssomnia:

Depression: 17,540 reports
Antidepressant therapy: 17,500 reports
Pain exacerbated: 13,668 reports
Rheumatoid arthritis aggravated: 13,625 reports
Pain relief: 13,485 reports
Ms hug: 12,998 reports
Hypertension: 12,107 reports
Htn: 12,061 reports
Anxiety aggravated: 10,450 reports
Anxiety: 10,449 reports

Browse all the conditions that are associated with Dyssomnia:

Dyssomnia (5,212 conditions)

Drugs similar to Oxycodone and Dyssomnia :

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride (the active ingredients of Oxycodone) and Oxycodone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.