Oxycodone and Endolymphatic hydrops - a phase IV clinical study of FDA data

Summary:

Endolymphatic hydrops is reported as a side effect among people who take Oxycodone (oxycodone hydrochloride), especially for people who are female, 60+ old, also take Acyclovir, and have Heart disease.

The phase IV clinical study analyzes which people have Endolymphatic hydrops when taking Oxycodone. It is created by eHealthMe based on reports of 159,853 people who have side effects when taking Oxycodone from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,583 Oxycodone users. Check the latest studies of Oxycodone.

What is Endolymphatic hydrops?

Endolymphatic hydrops (disorder of the inner ear) is found to be associated with 694 drugs and 640 conditions by eHealthMe. Check the latest studies of Endolymphatic hydrops.

On Oct, 15, 2025

159,853 people reported to have side effects when taking Oxycodone.
Among them, 41 people (0.03%) have Endolymphatic hydrops.

Could Oxycodone cause Endolymphatic hydrops?

Among these 41 people:

What is the gender of people who have Endolymphatic hydrops when taking Oxycodone? *

female: 60.53 %
male: 39.47 %

What is the age of people who have Endolymphatic hydrops when taking Oxycodone? *

What are other drugs people take besides Oxycodone? *

What are other side effects people have besides Endolymphatic hydrops? *

Dizziness: 30 people, 73.17%
Fatigue (feeling of tiredness): 23 people, 56.10%
Joint Pain: 21 people, 51.22%
Nausea (feeling of having an urge to vomit): 21 people, 51.22%
Pneumonia: 21 people, 51.22%
High Blood Pressure: 20 people, 48.78%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 20 people, 48.78%
Headache (pain in head): 20 people, 48.78%
Oropharyngeal Pain: 19 people, 46.34%
Muscle Aches (muscle pain): 19 people, 46.34%

What are the existing conditions these people have? *

Carcinoid Tumor: 7 people, 17.07%
Heart Disease: 7 people, 17.07%
Migraine (headache): 5 people, 12.20%
Breakthrough Pain: 4 people, 9.76%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 4 people, 9.76%
Neuropathy Peripheral (surface nerve damage): 4 people, 9.76%
Menopause (end of monthly cycles in women): 3 people, 7.32%
Upper Respiratory Tract Infection: 2 people, 4.88%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 4.88%
Immunodeficiency: 2 people, 4.88%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and have Endolymphatic hydrops?

- Check whether Endolymphatic hydrops is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycodone:

Oxycodone (162,583 reports)

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Endolymphatic hydrops:

Endolymphatic hydrops (694 drugs)

Browse all the conditions that are associated with Endolymphatic hydrops:

Endolymphatic hydrops (640 conditions)

Drugs similar to Oxycodone and Endolymphatic hydrops :

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride (the active ingredients of Oxycodone) and Oxycodone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.