Oxycodone and Fibromyalgia - a phase IV clinical study of FDA data

Summary:

Fibromyalgia is reported as a side effect among people who take Oxycodone (oxycodone hydrochloride), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Prednisone, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Fibromyalgia when taking Oxycodone. It is created by eHealthMe based on reports of 159,853 people who have side effects when taking Oxycodone from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,581 Oxycodone users. Check the latest studies of Oxycodone.

What is Fibromyalgia?

Fibromyalgia (a long-term condition which causes pain all over the body) is found to be associated with 1,345 drugs and 1,811 conditions by eHealthMe. Check the latest studies of Fibromyalgia.

On Aug, 26, 2025

159,853 people reported to have side effects when taking Oxycodone.
Among them, 1,662 people (1.04%) have Fibromyalgia.

Among these 1,662 people:

How long have people been on Oxycodone when they have Fibromyalgia? *

What is the gender of people who have Fibromyalgia when taking Oxycodone? *

female: 93.65 %
male: 6.35 %

What is the age of people who have Fibromyalgia when taking Oxycodone? *

What are other drugs people take besides Oxycodone? *

What are other side effects people have besides Fibromyalgia? *

Fatigue (feeling of tiredness): 1,048 people, 63.06%
Joint Pain: 941 people, 56.62%
Diarrhea: 876 people, 52.71%
Duodenal Ulcer Perforation (untreated ulcer can burn through the wall of the stomach): 837 people, 50.36%
Drug Ineffective: 836 people, 50.30%
Weakness: 806 people, 48.50%
General Physical Health Deterioration (weak health status): 801 people, 48.19%
Hair Loss: 788 people, 47.41%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 787 people, 47.35%
Folliculitis (infection of hair root): 780 people, 46.93%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1,078 people, 64.86%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 721 people, 43.38%
Psoriasis (immune-mediated disease that affects the skin): 325 people, 19.55%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 310 people, 18.65%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 177 people, 10.65%
Stress And Anxiety: 177 people, 10.65%
Inflammation: 152 people, 9.15%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 143 people, 8.60%
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 117 people, 7.04%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 116 people, 6.98%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and have Fibromyalgia?

- Check whether Fibromyalgia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycodone:

Oxycodone (162,581 reports)

Fibromyalgia treatments and more:

Fibromyalgia (92,966 reports)

How severe was Fibromyalgia and when was it recovered:

Fibromyalgia in Oxycodone

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fibromyalgia:

Fibromyalgia (1,345 drugs)

Browse all the conditions that are associated with Fibromyalgia:

Fibromyalgia (1,811 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride (the active ingredients of Oxycodone) and Oxycodone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.