Oxycodone and Leukocytoclastic vasculitis - a phase IV clinical study of FDA data

Summary:

Leukocytoclastic vasculitis is reported as a side effect among people who take Oxycodone (oxycodone hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Oxycontin, and have Hyperparathyroidism secondary.

The phase IV clinical study analyzes which people have Leukocytoclastic vasculitis when taking Oxycodone. It is created by eHealthMe based on reports of 159,853 people who have side effects when taking Oxycodone from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,592 Oxycodone users. Check the latest studies of Oxycodone.

What is Leukocytoclastic vasculitis?

Leukocytoclastic vasculitis (inflammation of small blood vessels (usually post-capillary venules in the dermis), characterized by palpable purpura) is found to be associated with 307 drugs and 675 conditions by eHealthMe. Check the latest studies of Leukocytoclastic vasculitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

159,853 people reported to have side effects when taking Oxycodone.
Among them, 20 people (0.01%) have Leukocytoclastic vasculitis.

Could Oxycodone cause Leukocytoclastic vasculitis?

Among these 20 people:

How long have people been on Oxycodone when they have Leukocytoclastic vasculitis? *

What is the gender of people who have Leukocytoclastic vasculitis when taking Oxycodone? *

female: 50 %
male: 50 %

What is the age of people who have Leukocytoclastic vasculitis when taking Oxycodone? *

What are other drugs people take besides Oxycodone? *

What are other side effects people have besides Leukocytoclastic vasculitis? *

Fall: 4 people, 20.00%
Nausea (feeling of having an urge to vomit): 4 people, 20.00%
Actinic Keratosis (skin disease due to sun exposure): 3 people, 15.00%
Lentigo (a small pigmented spot on the skin with a clearly-defined edge, surrounded by normal-appearing skin): 3 people, 15.00%
Cholecystitis (infection of gallbladder): 3 people, 15.00%
Pulmonary Embolism (blockage of the main artery of the lung): 3 people, 15.00%
Pericardial Effusion (fluid around the heart): 3 people, 15.00%
Oedema Peripheral (superficial swelling): 3 people, 15.00%
Drug Hypersensitivity: 3 people, 15.00%
Drug Ineffective: 3 people, 15.00%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 15.00%
Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 3 people, 15.00%
Procedural Pain: 2 people, 10.00%
High Blood Pressure: 2 people, 10.00%
Staphylococcal Infection (an infection with staphylococcus bacteria): 1 person, 5.00%
Squamous Cell Carcinoma (a cancer of a kind of epithelial cell): 1 person, 5.00%
Neoplasm Malignant (cancer tumour): 1 person, 5.00%
Multiple Myeloma (cancer of the plasma cells): 1 person, 5.00%
Metastases To Liver (cancer spreads to liver): 1 person, 5.00%
Enlarged Prostate: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and have Leukocytoclastic vasculitis?

- Check whether Leukocytoclastic vasculitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycodone:

Oxycodone (162,592 reports)

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Leukocytoclastic vasculitis:

Leukocytoclastic vasculitis (307 drugs)

Browse all the conditions that are associated with Leukocytoclastic vasculitis:

Leukocytoclastic vasculitis (675 conditions)

Related publications that referenced our studies

Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .
Alokaily FA, Alghamdi M, Almalki AS, Alhussaini H, "Aspirin induced leukocytoclastic vasculitis, lower gastrointestinal hemorrhage and acute renal failure (mimicking systemic vasculitis)", Saudi medical journal, 2013 Apr .
Ayturk S, Demir MV, Yaylac? S, Tamer A, "Propylthiouracil induced leukocytoclastic vasculitis: A rare manifestation", Indian journal of endocrinology and metabolism, 2013 Jan .
Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .
Alokaily FA, Alghamdi M, Almalki AS, Alhussaini H, "Aspirin induced leukocytoclastic vasculitis, lower gastrointestinal hemorrhage and acute renal failure (mimicking systemic vasculitis)", Saudi medical journal, 2013 Apr .
Ayturk S, Demir MV, Yaylac? S, Tamer A, "Propylthiouracil induced leukocytoclastic vasculitis: A rare manifestation", Indian journal of endocrinology and metabolism, 2013 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride (the active ingredients of Oxycodone) and Oxycodone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.