Oxycodone and Nodule - a phase IV clinical study of FDA data

Summary:

Nodule is reported as a side effect among people who take Oxycodone (oxycodone hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Prednisone, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Nodule when taking Oxycodone. It is created by eHealthMe based on reports of 159,853 people who have side effects when taking Oxycodone from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,583 Oxycodone users. Check the latest studies of Oxycodone.

What is Nodule?

Nodule (a growth of abnormal tissue) is found to be associated with 1,069 drugs and 862 conditions by eHealthMe. Check the latest studies of Nodule.

On Aug, 17, 2025

159,853 people reported to have side effects when taking Oxycodone.
Among them, 250 people (0.16%) have Nodule.

Among these 250 people:

How long have people been on Oxycodone when they have Nodule? *

What is the gender of people who have Nodule when taking Oxycodone? *

female: 86.1 %
male: 13.9 %

What is the age of people who have Nodule when taking Oxycodone? *

What are other drugs people take besides Oxycodone? *

What are other side effects people have besides Nodule? *

Joint Pain: 143 people, 57.20%
Pneumonia: 109 people, 43.60%
Fatigue (feeling of tiredness): 101 people, 40.40%
Drug Ineffective: 94 people, 37.60%
Pain In Extremity: 91 people, 36.40%
Fibromyalgia (a long-term condition which causes pain all over the body): 89 people, 35.60%
Rashes (redness): 89 people, 35.60%
Urinary Tract Infection: 85 people, 34.00%
Nausea (feeling of having an urge to vomit): 85 people, 34.00%
Dyspnea (difficult or laboured breathing): 85 people, 34.00%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 122 people, 48.80%
Depression: 27 people, 10.80%
Inflammation: 23 people, 9.20%
Fibromyalgia (a long-term condition which causes pain all over the body): 23 people, 9.20%
Hypersensitivity: 21 people, 8.40%
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 21 people, 8.40%
Insomnia (sleeplessness): 20 people, 8.00%
Stress And Anxiety: 19 people, 7.60%
Diabetes: 16 people, 6.40%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 15 people, 6.00%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and have Nodule?

- Check whether Nodule is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycodone:

Oxycodone (162,583 reports)

Nodule treatments and more:

Nodule (15,836 reports)

Common Oxycodone side effects:

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Nodule:

Browse all the drugs that are associated with Nodule:

Nodule (1,069 drugs)

Common conditions associated with Nodule:

Ra: 5,077 reports
Alternative medicine - pain relief: 670 reports
High blood pressure: 660 reports
Psoriasis: 590 reports
Osteoporosis: 537 reports
Psoriatic arthropathy aggravated: 489 reports
Chronic asthma: 472 reports
Crohns: 415 reports
Blood triglycerides increased: 401 reports
Type 2 diabetes: 344 reports

Browse all the conditions that are associated with Nodule:

Nodule (862 conditions)

Drugs similar to Oxycodone and Nodule :

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride (the active ingredients of Oxycodone) and Oxycodone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.