Oxycodone and Proctalgia - a phase IV clinical study of FDA data

Summary:

Proctalgia is reported as a side effect among people who take Oxycodone (oxycodone hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Vitamin B12, and have Crohn's disease.

The phase IV clinical study analyzes which people have Proctalgia when taking Oxycodone. It is created by eHealthMe based on reports of 159,853 people who have side effects when taking Oxycodone from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,591 Oxycodone users. Check the latest studies of Oxycodone.

What is Proctalgia?

Proctalgia (pain in the rectum) is found to be associated with 803 drugs and 767 conditions by eHealthMe. Check the latest studies of Proctalgia.

On Jan, 02, 2026

159,853 people reported to have side effects when taking Oxycodone.
Among them, 159 people (0.1%) have Proctalgia.

Among these 159 people:

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and have Proctalgia?

- Check whether Proctalgia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycodone:

Oxycodone (162,591 reports)

Proctalgia treatments and more:

Proctalgia (9,250 reports)

How severe was Proctalgia and when was it recovered:

Proctalgia in Oxycodone

Expand to all the drugs that have ingredients of oxycodone hydrochloride:

Proctalgia and drugs with ingredients of oxycodone hydrochloride (233 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Proctalgia:

Proctalgia (803 drugs)

Browse all the conditions that are associated with Proctalgia:

Proctalgia (767 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride (the active ingredients of Oxycodone) and Oxycodone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.