Oxycodone and Progressive multiple sclerosis - a phase IV clinical study of FDA data

Summary:

Progressive multiple sclerosis is reported as a side effect among people who take Oxycodone (oxycodone hydrochloride), especially for people who are female, 50-59 old, also take Vitamin D3, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Progressive multiple sclerosis when taking Oxycodone. It is created by eHealthMe based on reports of 159,853 people who have side effects when taking Oxycodone from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,592 Oxycodone users. Check the latest studies of Oxycodone.

What is Progressive multiple sclerosis?

Progressive multiple sclerosis (chronic autoimmune disease of the central nervous system in which gradual destruction of myelin occurs in patches throughout the brain or spinal cord) is found to be associated with 105 drugs and 114 conditions by eHealthMe. Check the latest studies of Progressive multiple sclerosis.

On Feb, 03, 2026

159,853 people reported to have side effects when taking Oxycodone.
Among them, 15 people (0.01%) have Progressive multiple sclerosis.

Could Oxycodone cause Progressive multiple sclerosis?

Among these 15 people:

What is the gender of people who have Progressive multiple sclerosis when taking Oxycodone? *

female: 64.29 %
male: 35.71 %

What is the age of people who have Progressive multiple sclerosis when taking Oxycodone? *

What are other drugs people take besides Oxycodone? *

What are other side effects people have besides Progressive multiple sclerosis? *

Muscle Spasms (muscle contraction): 7 people, 46.67%
Dyspnea (difficult or laboured breathing): 6 people, 40.00%
Drug Ineffective: 6 people, 40.00%
Drowsiness: 6 people, 40.00%
Memory Loss: 5 people, 33.33%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 5 people, 33.33%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 5 people, 33.33%
Urinary Incontinence (inability to control the flow of urine and involuntary urination): 5 people, 33.33%
Tremor (trembling or shaking movements in one or more parts of your body): 5 people, 33.33%
Muscle Aches (muscle pain): 4 people, 26.67%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 12 people, 80.00%
Primary Progressive Multiple Sclerosis (primary progressive inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 20.00%
Joint Pain: 3 people, 20.00%
Muscle Spasms (muscle contraction): 3 people, 20.00%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 3 people, 20.00%
Nausea (feeling of having an urge to vomit): 3 people, 20.00%
Weakness: 3 people, 20.00%
Inflammation: 2 people, 13.33%
Nausea And Vomiting: 2 people, 13.33%
Allergic Rhinitis: 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and have Progressive multiple sclerosis?

- Check whether Progressive multiple sclerosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycodone:

Oxycodone (162,592 reports)

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Progressive multiple sclerosis:

Progressive multiple sclerosis (105 drugs)

Browse all the conditions that are associated with Progressive multiple sclerosis:

Progressive multiple sclerosis (114 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride (the active ingredients of Oxycodone) and Oxycodone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.