Oxycodone and Ptsd - a phase IV clinical study of FDA data

Summary:

Ptsd is reported as a side effect among people who take Oxycodone (oxycodone hydrochloride), especially for people who are male, 50-59 old, have been taking the drug for 2 - 5 years also take Oxycontin, and have Stress and anxiety.

The phase IV clinical study analyzes which people have Ptsd when taking Oxycodone. It is created by eHealthMe based on reports of 159,853 people who have side effects when taking Oxycodone from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,583 Oxycodone users. Check the latest studies of Oxycodone.

What is Ptsd?

Ptsd (post-traumatic stress disorder) is found to be associated with 868 drugs and 921 conditions by eHealthMe. Check the latest studies of Ptsd.

On Oct, 08, 2025

159,853 people reported to have side effects when taking Oxycodone.
Among them, 306 people (0.19%) have Ptsd.

Among these 306 people:

How long have people been on Oxycodone when they have Ptsd? *

What is the gender of people who have Ptsd when taking Oxycodone? *

female: 46.15 %
male: 53.85 %

What is the age of people who have Ptsd when taking Oxycodone? *

What are other drugs people take besides Oxycodone? *

Oxycontin: 143 people, 46.73%
Hydrocodone Bitartrate And Acetaminophen: 109 people, 35.62%
Dilaudid: 89 people, 29.08%
Morphine Sulfate: 89 people, 29.08%
Ms Contin: 74 people, 24.18%
Tramadol: 73 people, 23.86%
Percocet: 46 people, 15.03%
Buprenorphine: 43 people, 14.05%
Vicodin: 40 people, 13.07%
Hydromorphone Hydrochloride: 34 people, 11.11%

What are other side effects people have besides Ptsd? *

Drug Dependence: 170 people, 55.56%
Stress And Anxiety: 142 people, 46.41%
Depression: 140 people, 45.75%
Overdose: 99 people, 32.35%
Emotional Distress: 65 people, 21.24%
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 64 people, 20.92%
Suicidal Ideation: 48 people, 15.69%
Memory Loss: 36 people, 11.76%
Insomnia (sleeplessness): 35 people, 11.44%
Fatigue (feeling of tiredness): 35 people, 11.44%

What are the existing conditions these people have? *

Stress And Anxiety: 16 people, 5.23%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 14 people, 4.58%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 14 people, 4.58%
Depression: 11 people, 3.59%
Bipolar Disorder (mood disorder): 10 people, 3.27%
Migraine (headache): 8 people, 2.61%
Hiv Infection: 7 people, 2.29%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 2.29%
Fibromyalgia (a long-term condition which causes pain all over the body): 7 people, 2.29%
High Blood Pressure: 6 people, 1.96%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and have Ptsd?

- Check whether Ptsd is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycodone:

Oxycodone (162,583 reports)

Ptsd treatments and more:

Ptsd (20,315 reports)

Common Oxycodone side effects:

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Ptsd:

Browse all the drugs that are associated with Ptsd:

Ptsd (868 drugs)

Common conditions associated with Ptsd:

Browse all the conditions that are associated with Ptsd:

Ptsd (921 conditions)

Drugs similar to Oxycodone and Ptsd :

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride (the active ingredients of Oxycodone) and Oxycodone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.