Oxycodone and Sinus node dysfunction - a phase IV clinical study of FDA data

Summary:

Sinus node dysfunction is reported as a side effect among people who take Oxycodone (oxycodone hydrochloride), especially for people who are male, 60+ old, also take Ambien, and have Constipation.

The phase IV clinical study analyzes which people have Sinus node dysfunction when taking Oxycodone. It is created by eHealthMe based on reports of 159,853 people who have side effects when taking Oxycodone from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,592 Oxycodone users. Check the latest studies of Oxycodone.

What is Sinus node dysfunction?

Sinus node dysfunction (a group of abnormal heart rhythms) is found to be associated with 1,148 drugs and 842 conditions by eHealthMe. Check the latest studies of Sinus node dysfunction.

On Apr, 19, 2026

159,853 people reported to have side effects when taking Oxycodone.
Among them, 29 people (0.02%) have Sinus node dysfunction.

Could Oxycodone cause Sinus node dysfunction?

Among these 29 people:

What is the gender of people who have Sinus node dysfunction when taking Oxycodone? *

female: 25 %
male: 75 %

What is the age of people who have Sinus node dysfunction when taking Oxycodone? *

What are other drugs people take besides Oxycodone? *

What are other side effects people have besides Sinus node dysfunction? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 19 people, 65.52%
Fatigue (feeling of tiredness): 18 people, 62.07%
Pleural Effusion (water on the lungs): 16 people, 55.17%
Stress And Anxiety: 15 people, 51.72%
Fall: 14 people, 48.28%
Nausea And Vomiting: 13 people, 44.83%
Nausea (feeling of having an urge to vomit): 13 people, 44.83%
Injury: 13 people, 44.83%
Pain In Jaw: 12 people, 41.38%
Balance Disorder: 12 people, 41.38%

What are the existing conditions these people have? *

Constipation: 8 people, 27.59%
Non-Small Cell Lung Cancer Recurrent (type of epithelial lung cancer reoccurrence): 3 people, 10.34%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 2 people, 6.90%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 2 people, 6.90%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 6.90%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 6.90%
Type 2 Diabetes: 1 person, 3.45%
Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 1 person, 3.45%
Breast Cancer Metastatic: 1 person, 3.45%
Heart Rate Increased: 1 person, 3.45%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and have Sinus node dysfunction?

- Check whether Sinus node dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycodone:

Oxycodone (162,592 reports)

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sinus node dysfunction:

Sinus node dysfunction (1,148 drugs)

Browse all the conditions that are associated with Sinus node dysfunction:

Sinus node dysfunction (842 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride (the active ingredients of Oxycodone) and Oxycodone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.