Oxycodone and Thin bones - a phase IV clinical study of FDA data

Summary:

Thin bones is reported as a side effect among people who take Oxycodone (oxycodone hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Zometa, and have Hiv infection.

The phase IV clinical study analyzes which people have Thin bones when taking Oxycodone. It is created by eHealthMe based on reports of 159,853 people who have side effects when taking Oxycodone from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,586 Oxycodone users. Check the latest studies of Oxycodone.

What is Thin bones?

Thin bones is found to be associated with 2,551 drugs and 1,908 conditions by eHealthMe. Check the latest studies of Thin bones.



On Aug, 08, 2025

159,853 people reported to have side effects when taking Oxycodone.
Among them, 1,049 people (0.66%) have Thin bones.

Could Oxycodone cause Thin bones?

Among these 1,049 people:

How long have people been on Oxycodone when they have Thin bones? *

  • < 1 month: 30.77 %
  • 1 - 6 months: 33.33 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 20.51 %
  • 2 - 5 years: 12.82 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 2.56 %

What is the gender of people who have Thin bones when taking Oxycodone? *

  • female: 65.05 %
  • male: 34.95 %

What is the age of people who have Thin bones when taking Oxycodone? *

  • 0-1: 0.13 %
  • 2-9: 0.13 %
  • 10-19: 0.53 %
  • 20-29: 0.92 %
  • 30-39: 4.47 %
  • 40-49: 21.58 %
  • 50-59: 32.76 %
  • 60+: 39.47 %

What are other drugs people take besides Oxycodone? *

  1. Zometa: 287 people, 27.36%
  2. Prednisone: 266 people, 25.36%
  3. Pantoprazole: 240 people, 22.88%
  4. Aredia: 207 people, 19.73%
  5. Oxycontin: 192 people, 18.30%
  6. Truvada: 190 people, 18.11%
  7. Morphine: 185 people, 17.64%
  8. Aspirin: 176 people, 16.78%
  9. Albuterol: 167 people, 15.92%
  10. Colace: 161 people, 15.35%

What are other side effects people have besides Thin bones? *

  1. Stress And Anxiety: 540 people, 51.48%
  2. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 365 people, 34.80%
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable): 347 people, 33.08%
  4. Emotional Distress: 340 people, 32.41%
  5. Depression: 306 people, 29.17%
  6. Osteopenia (a condition where bone mineral density is lower than normal): 284 people, 27.07%
  7. Dyspnea (difficult or laboured breathing): 283 people, 26.98%
  8. Fatigue (feeling of tiredness): 271 people, 25.83%
  9. Weakness: 270 people, 25.74%
  10. Joint Pain: 265 people, 25.26%

What are the existing conditions these people have? *

  1. Hiv Infection: 272 people, 25.93%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 97 people, 9.25%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 95 people, 9.06%
  4. Depression: 79 people, 7.53%
  5. Multiple Myeloma (cancer of the plasma cells): 78 people, 7.44%
  6. High Blood Pressure: 77 people, 7.34%
  7. Stress And Anxiety: 69 people, 6.58%
  8. Seasonal Allergy (allergic condition due to certain season): 55 people, 5.24%
  9. High Blood Cholesterol: 53 people, 5.05%
  10. Muscle Spasms (muscle contraction): 52 people, 4.96%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and have Thin bones?

- Check whether Thin bones is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycodone:

Thin bones treatments and more:

How severe was Thin bones and when was it recovered:

Expand to all the drugs that have ingredients of oxycodone hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Oxycodone side effects:

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Thin bones:

Browse all the drugs that are associated with Thin bones:

Common conditions associated with Thin bones:

Browse all the conditions that are associated with Thin bones:

Drugs similar to Oxycodone and Thin bones :


How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride (the active ingredients of Oxycodone) and Oxycodone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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