Oxycodone and Underactive thyroid - a phase IV clinical study of FDA data

Summary:

Underactive thyroid is reported as a side effect among people who take Oxycodone (oxycodone hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Synthroid, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Underactive thyroid when taking Oxycodone. It is created by eHealthMe based on reports of 159,853 people who have side effects when taking Oxycodone from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,586 Oxycodone users. Check the latest studies of Oxycodone.

What is Underactive thyroid?

Underactive thyroid is found to be associated with 2,782 drugs and 2,609 conditions by eHealthMe. Check the latest studies of Underactive thyroid.



On Oct, 19, 2025

159,853 people reported to have side effects when taking Oxycodone.
Among them, 445 people (0.28%) have Underactive thyroid.

Could Oxycodone cause Underactive thyroid?

Among these 445 people:

How long have people been on Oxycodone when they have Underactive thyroid? *

  • < 1 month: 60 %
  • 1 - 6 months: 20 %
  • 6 - 12 months: 4 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 16 %
  • 10+ years: 0.0 %

What is the gender of people who have Underactive thyroid when taking Oxycodone? *

  • female: 66.67 %
  • male: 33.33 %

What is the age of people who have Underactive thyroid when taking Oxycodone? *

  • 0-1: 0.0 %
  • 2-9: 0.29 %
  • 10-19: 0.57 %
  • 20-29: 1.43 %
  • 30-39: 6.3 %
  • 40-49: 19.48 %
  • 50-59: 25.21 %
  • 60+: 46.7 %

What are other drugs people take besides Oxycodone? *

  1. Synthroid: 119 people, 26.74%
  2. Prednisone: 74 people, 16.63%
  3. Metformin: 67 people, 15.06%
  4. Gabapentin: 65 people, 14.61%
  5. Zometa: 63 people, 14.16%
  6. Lasix: 59 people, 13.26%
  7. Ambien: 55 people, 12.36%
  8. Tylenol: 54 people, 12.13%
  9. Acetaminophen: 53 people, 11.91%
  10. Actemra: 51 people, 11.46%

What are other side effects people have besides Underactive thyroid? *

  1. High Blood Pressure: 125 people, 28.09%
  2. Joint Pain: 113 people, 25.39%
  3. Fatigue (feeling of tiredness): 103 people, 23.15%
  4. Diarrhea: 97 people, 21.80%
  5. Weight Decreased: 92 people, 20.67%
  6. Anaemia (lack of blood): 90 people, 20.22%
  7. Stress And Anxiety: 89 people, 20.00%
  8. Urinary Tract Infection: 87 people, 19.55%
  9. Fall: 86 people, 19.33%
  10. Nausea (feeling of having an urge to vomit): 85 people, 19.10%

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 72 people, 16.18%
  2. High Blood Pressure: 36 people, 8.09%
  3. Stress And Anxiety: 34 people, 7.64%
  4. Constipation: 32 people, 7.19%
  5. Nausea (feeling of having an urge to vomit): 30 people, 6.74%
  6. Depression: 30 people, 6.74%
  7. Dyspnea (difficult or laboured breathing): 23 people, 5.17%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 21 people, 4.72%
  9. Insomnia (sleeplessness): 21 people, 4.72%
  10. Lung Cancer - Non-Small Cell (lung cancer): 18 people, 4.04%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and have Underactive thyroid?

- Check whether Underactive thyroid is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycodone:

Underactive thyroid treatments and more:

How severe was Underactive thyroid and when was it recovered:

Expand to all the drugs that have ingredients of oxycodone hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Oxycodone side effects:

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Underactive thyroid:

Browse all the drugs that are associated with Underactive thyroid:

Common conditions associated with Underactive thyroid:

Browse all the conditions that are associated with Underactive thyroid:

Drugs similar to Oxycodone and Underactive thyroid :


How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride (the active ingredients of Oxycodone) and Oxycodone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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