Oxycontin and Hypotonia - a phase IV clinical study of FDA data

Summary:

Hypotonia is reported as a side effect among people who take Oxycontin (oxycodone hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Neurontin, and have Muscle spasticity.

The phase IV clinical study analyzes which people have Hypotonia when taking Oxycontin. It is created by eHealthMe based on reports of 210,595 people who have side effects when taking Oxycontin from the FDA, and is updated regularly.

What is Oxycontin?

Oxycontin has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 212,533 Oxycontin users. Check the latest studies of Oxycontin.

What is Hypotonia?

Hypotonia (low muscle tone) is found to be associated with 827 drugs and 1,770 conditions by eHealthMe. Check the latest studies of Hypotonia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

210,595 people reported to have side effects when taking Oxycontin.
Among them, 49 people (0.02%) have Hypotonia.

Among these 49 people:

How long have people been on Oxycontin when they have Hypotonia? *

What is the gender of people who have Hypotonia when taking Oxycontin? *

female: 48.98 %
male: 51.02 %

What is the age of people who have Hypotonia when taking Oxycontin? *

What are other drugs people take besides Oxycontin? *

Neurontin: 8 people, 16.33%
Hydrocodone Bitartrate And Acetaminophen: 7 people, 14.29%
Percocet: 7 people, 14.29%
Dilaudid: 5 people, 10.20%
Xanax: 5 people, 10.20%
Butrans: 4 people, 8.16%
Buspar: 4 people, 8.16%
Morphine: 4 people, 8.16%
Prozac: 4 people, 8.16%
Ms Contin: 4 people, 8.16%

What are other side effects people have besides Hypotonia? *

Drug Dependence: 17 people, 34.69%
Weakness: 13 people, 26.53%
Stress And Anxiety: 12 people, 24.49%
Memory Loss: 12 people, 24.49%
Constipation: 12 people, 24.49%
Drowsiness: 11 people, 22.45%
Nausea (feeling of having an urge to vomit): 11 people, 22.45%
Disturbance In Attention: 10 people, 20.41%
Dizziness: 10 people, 20.41%
Depression: 10 people, 20.41%

What are the existing conditions these people have? *

Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 3 people, 6.12%
Renal Cancer Stage Iv (the tumour has spread to areas beyond gerota's fascia and extends into the adrenal gland on the same side of the body as the tumour, possibly to lymph nodes, but not to other parts of the body): 2 people, 4.08%
Spinal Cord Trauma: 2 people, 4.08%
Sleep Disorder: 2 people, 4.08%
Back Injury: 2 people, 4.08%
Neck Injury: 2 people, 4.08%
Drug Dependence: 1 person, 2.04%
High Blood Pressure: 1 person, 2.04%
Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 2.04%
Encephalopathy (functioning of the brain is affected by some agent or condition): 1 person, 2.04%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycontin and have Hypotonia?

- Check whether Hypotonia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycontin:

Oxycontin (212,533 reports)

Hypotonia treatments and more:

Hypotonia (14,614 reports)

Browse all side effects of Oxycontin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypotonia:

Hypotonia (827 drugs)

Browse all the conditions that are associated with Hypotonia:

Hypotonia (1,770 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride (the active ingredients of Oxycontin) and Oxycontin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.