Oxycontin and Suicidal behaviour - a phase IV clinical study of FDA data

Summary:

Suicidal behaviour is reported as a side effect among people who take Oxycontin (oxycodone hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Hydrocodone Bitartrate And Acetaminophen, and have Breakthrough pain.

The phase IV clinical study analyzes which people have Suicidal behaviour when taking Oxycontin. It is created by eHealthMe based on reports of 210,595 people who have side effects when taking Oxycontin from the FDA, and is updated regularly.

What is Oxycontin?

Oxycontin has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 212,532 Oxycontin users. Check the latest studies of Oxycontin.

What is Suicidal behaviour?

Suicidal behaviour is found to be associated with 523 drugs and 506 conditions by eHealthMe. Check the latest studies of Suicidal behaviour.

On Sep, 20, 2025

210,595 people reported to have side effects when taking Oxycontin.
Among them, 179 people (0.08%) have Suicidal behaviour.

Could Oxycontin cause Suicidal behaviour?

Among these 179 people:

How long have people been on Oxycontin when they have Suicidal behaviour? *

What is the gender of people who have Suicidal behaviour when taking Oxycontin? *

female: 29.94 %
male: 70.06 %

What is the age of people who have Suicidal behaviour when taking Oxycontin? *

What are other drugs people take besides Oxycontin? *

Hydrocodone Bitartrate And Acetaminophen: 69 people, 38.55%
Dilaudid: 58 people, 32.40%
Ms Contin: 37 people, 20.67%
Vicodin: 20 people, 11.17%
Butrans: 19 people, 10.61%
Percocet: 15 people, 8.38%
Suboxone: 10 people, 5.59%
Oxycodone Hydrochloride: 9 people, 5.03%
Xanax: 8 people, 4.47%
Ambien: 7 people, 3.91%

What are other side effects people have besides Suicidal behaviour? *

Drug Dependence: 139 people, 77.65%
Overdose: 81 people, 45.25%
Depression: 77 people, 43.02%
Stress And Anxiety: 46 people, 25.70%
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 38 people, 21.23%
Emotional Distress: 32 people, 17.88%
Withdrawal Syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance): 26 people, 14.53%
Nausea (feeling of having an urge to vomit): 18 people, 10.06%
Memory Loss: 17 people, 9.50%
Fatigue (feeling of tiredness): 16 people, 8.94%

What are the existing conditions these people have? *

Stress And Anxiety: 5 people, 2.79%
Breakthrough Pain: 5 people, 2.79%
Depression: 4 people, 2.23%
Insomnia (sleeplessness): 3 people, 1.68%
Facial Pain: 3 people, 1.68%
Headache (pain in head): 3 people, 1.68%
Sleep Disorder: 3 people, 1.68%
Intervertebral Disc Degeneration (spinal disc degeneration): 3 people, 1.68%
Back Disorder: 2 people, 1.12%
Tendon Injury: 2 people, 1.12%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycontin and have Suicidal behaviour?

- Check whether Suicidal behaviour is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycontin:

Oxycontin (212,532 reports)

Common Oxycontin side effects:

Browse all side effects of Oxycontin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Suicidal behaviour:

Browse all the drugs that are associated with Suicidal behaviour:

Suicidal behaviour (523 drugs)

Common conditions associated with Suicidal behaviour:

Depression: 719 reports
Tobacco abuse: 344 reports
Stress: 323 reports
Pain: 211 reports
Bipolar disorder: 202 reports
Attention deficit hyperactivity disorder (adhd): 162 reports
Asthma: 152 reports
Multiple sclerosis: 134 reports
Sleep issues: 130 reports
Major depression: 102 reports

Browse all the conditions that are associated with Suicidal behaviour:

Suicidal behaviour (506 conditions)

Drugs similar to Oxycontin and Suicidal behaviour :

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride (the active ingredients of Oxycontin) and Oxycontin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.