Oxycontin and Underactive thyroid - a phase IV clinical study of FDA data

Summary:

Underactive thyroid is reported as a side effect among people who take Oxycontin (oxycodone hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Zometa, and have Renal cell carcinoma.

The phase IV clinical study analyzes which people have Underactive thyroid when taking Oxycontin. It is created by eHealthMe based on reports of 210,595 people who have side effects when taking Oxycontin from the FDA, and is updated regularly.

What is Oxycontin?

Oxycontin has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 212,532 Oxycontin users. Check the latest studies of Oxycontin.

What is Underactive thyroid?

Underactive thyroid is found to be associated with 2,781 drugs and 2,609 conditions by eHealthMe. Check the latest studies of Underactive thyroid.



On Oct, 25, 2025

210,595 people reported to have side effects when taking Oxycontin.
Among them, 337 people (0.16%) have Underactive thyroid.

Could Oxycontin cause Underactive thyroid?

Among these 337 people:

How long have people been on Oxycontin when they have Underactive thyroid? *

  • < 1 month: 55.81 %
  • 1 - 6 months: 18.6 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 18.6 %
  • 5 - 10 years: 2.33 %
  • 10+ years: 4.65 %

What is the gender of people who have Underactive thyroid when taking Oxycontin? *

  • female: 61.98 %
  • male: 38.02 %

What is the age of people who have Underactive thyroid when taking Oxycontin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 6.37 %
  • 40-49: 22.31 %
  • 50-59: 25.1 %
  • 60+: 46.22 %

What are other drugs people take besides Oxycontin? *

  1. Zometa: 82 people, 24.33%
  2. Ambien: 76 people, 22.55%
  3. Synthroid: 74 people, 21.96%
  4. Nexium: 72 people, 21.36%
  5. Celebrex: 66 people, 19.58%
  6. Prednisone: 60 people, 17.80%
  7. Lasix: 59 people, 17.51%
  8. Percocet: 58 people, 17.21%
  9. Lyrica: 56 people, 16.62%
  10. Neurontin: 52 people, 15.43%

What are other side effects people have besides Underactive thyroid? *

  1. Stress And Anxiety: 131 people, 38.87%
  2. High Blood Pressure: 98 people, 29.08%
  3. Depression: 97 people, 28.78%
  4. Oedema Peripheral (superficial swelling): 89 people, 26.41%
  5. Injury: 87 people, 25.82%
  6. Dyspnea (difficult or laboured breathing): 85 people, 25.22%
  7. Thrombocytopenia (decrease of platelets in blood): 83 people, 24.63%
  8. Anaemia (lack of blood): 81 people, 24.04%
  9. Fall: 80 people, 23.74%
  10. Pneumonia: 77 people, 22.85%

What are the existing conditions these people have? *

  1. Renal Cell Carcinoma (a kidney cancer): 29 people, 8.61%
  2. Constipation: 20 people, 5.93%
  3. Nausea (feeling of having an urge to vomit): 16 people, 4.75%
  4. Insomnia (sleeplessness): 16 people, 4.75%
  5. Osteoporosis (bones weak and more likely to break): 14 people, 4.15%
  6. Bone Loss: 14 people, 4.15%
  7. Neoplasm Malignant (cancer tumour): 13 people, 3.86%
  8. Lung Cancer - Non-Small Cell (lung cancer): 13 people, 3.86%
  9. Stress And Anxiety: 13 people, 3.86%
  10. Depression: 11 people, 3.26%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycontin and have Underactive thyroid?

- Check whether Underactive thyroid is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxycontin:

Underactive thyroid treatments and more:

How severe was Underactive thyroid and when was it recovered:

Expand to all the drugs that have ingredients of oxycodone hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Oxycontin side effects:

Browse all side effects of Oxycontin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Underactive thyroid:

Browse all the drugs that are associated with Underactive thyroid:

Common conditions associated with Underactive thyroid:

Browse all the conditions that are associated with Underactive thyroid:

Drugs similar to Oxycontin and Underactive thyroid :


How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride (the active ingredients of Oxycontin) and Oxycontin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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