Oxymorphone hydrochloride and Knee joint replacement - a phase IV clinical study of FDA data

Summary:

Knee joint replacement is reported as a side effect among people who take Oxymorphone hydrochloride (oxymorphone hydrochloride), especially for people who are male, also take Promethazine Hydrochloride And Codeine Phosphate,.

The phase IV clinical study analyzes which people have Knee joint replacement when taking Oxymorphone hydrochloride. It is created by eHealthMe based on reports of 12,307 people who have side effects when taking Oxymorphone hydrochloride from the FDA, and is updated regularly.

What is Oxymorphone hydrochloride?

Oxymorphone hydrochloride has active ingredients of oxymorphone hydrochloride. It is often used in chronic pain. eHealthMe is studying from 12,346 Oxymorphone hydrochloride users. Check the latest studies of Oxymorphone hydrochloride.

What is Knee joint replacement?

Knee joint replacement is found to be associated with 954 drugs and 1,228 conditions by eHealthMe. Check the latest studies of Knee joint replacement.

On Jul, 12, 2026

12,307 people reported to have side effects when taking Oxymorphone hydrochloride.
Among them, 15 people (0.12%) have Knee joint replacement.

Could Oxymorphone hydrochloride cause Knee joint replacement?

Among these 15 people:

What is the gender of people who have Knee joint replacement when taking Oxymorphone hydrochloride? *

female: 9.09 %
male: 90.91 %

What are other drugs people take besides Oxymorphone hydrochloride? *

Tramadol Hydrochloride: 15 people, 100.00%
Propoxyphene Hydrochloride: 15 people, 100.00%
Promethazine Hydrochloride And Codeine Phosphate: 15 people, 100.00%

What are other side effects people have besides Knee joint replacement? *

Spinal Osteoarthritis (joint cartilage loss in spine): 1 person, 6.67%
Spinal Cord Trauma: 1 person, 6.67%
Gun Shot Wound: 1 person, 6.67%
Back Pain: 1 person, 6.67%
Ankle Fracture: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Oxymorphone hydrochloride and have Knee joint replacement?

- Check whether Knee joint replacement is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Oxymorphone hydrochloride:

Oxymorphone hydrochloride (12,346 reports)

Browse all side effects of Oxymorphone hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Knee joint replacement:

Knee joint replacement (954 drugs)

Browse all the conditions that are associated with Knee joint replacement:

Knee joint replacement (1,228 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on oxymorphone hydrochloride (the active ingredients of Oxymorphone hydrochloride) and Oxymorphone hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.