Ozempic and Hiccups - a phase IV clinical study of FDA data
Summary:
Hiccups is reported as a side effect among people who take Ozempic (semaglutide), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Metformin, and have Type 2 diabetes.
The phase IV clinical study analyzes which people have Hiccups when taking Ozempic. It is created by eHealthMe based on reports of 28,954 people who have side effects when taking Ozempic from the FDA, and is updated regularly.
What is Ozempic?
Ozempic has active ingredients of semaglutide. It is often used in weight loss. eHealthMe is studying from 29,762 Ozempic users. Check the latest studies of Ozempic.
What is Hiccups?
Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough) is found to be associated with 697 drugs and 1,183 conditions by eHealthMe. Check the latest studies of Hiccups.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
28,954 people reported to have side effects when taking Ozempic.
Among them, 94 people (0.32%) have Hiccups.

Among these 94 people:
How long have people been on Ozempic when they have Hiccups? *
- < 1 month: 58.82 %
- 1 - 6 months: 17.65 %
- 6 - 12 months: 17.65 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 5.88 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Hiccups when taking Ozempic? *
- female: 30.77 %
- male: 69.23 %
What is the age of people who have Hiccups when taking Ozempic? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 2.17 %
- 40-49: 4.35 %
- 50-59: 21.74 %
- 60+: 71.74 %
What are other drugs people take besides Ozempic? *
- Metformin: 8 people, 8.51%
- Aspirin: 4 people, 4.26%
- Humalog: 3 people, 3.19%
- Basaglar: 2 people, 2.13%
- Novolog: 2 people, 2.13%
- Jardiance: 2 people, 2.13%
- Empagliflozin: 2 people, 2.13%
- Tresiba: 2 people, 2.13%
- Fiasp: 2 people, 2.13%
- Atorvastatin Calcium: 2 people, 2.13%
What are other side effects people have besides Hiccups? *
- Nausea (feeling of having an urge to vomit): 38 people, 40.43%
- Nausea And Vomiting: 19 people, 20.21%
- Indigestion: 15 people, 15.96%
- Belching (release of gas from the digestive tract): 15 people, 15.96%
- Diarrhea: 13 people, 13.83%
- Abdominal Pain Upper: 12 people, 12.77%
- Constipation: 11 people, 11.70%
- Blood Glucose Increased: 9 people, 9.57%
- Abdominal Distension: 9 people, 9.57%
- Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 9 people, 9.57%
What are the existing conditions these people have? *
- Type 2 Diabetes: 33 people, 35.11%
- Diabetes: 9 people, 9.57%
- Type 1 Diabetes: 2 people, 2.13%
- Glycosylated Haemoglobin Increased: 2 people, 2.13%
- Weight Decreased: 1 person, 1.06%
- Stress And Anxiety: 1 person, 1.06%
- Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 1.06%
- Quit Smoking: 1 person, 1.06%
- Heart Attack: 1 person, 1.06%
- Glucose Tolerance Impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis): 1 person, 1.06%
* Approximation only. Some reports may have incomplete information.
Do you take Ozempic and have Hiccups?
- Check whether Hiccups is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Ozempic:
- Ozempic (29,762 reports)
Hiccups treatments and more:
- Hiccups (10,644 reports)
How severe was Hiccups and when was it recovered:
Expand to all the drugs that have ingredients of semaglutide:
- Hiccups and drugs with ingredients of semaglutide (114 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ozempic:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Hiccups:
- Hiccups (697 drugs)
Browse all the conditions that are associated with Hiccups:
- Hiccups (1,183 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on semaglutide (the active ingredients of Ozempic) and Ozempic (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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