Ozempic and Liver disorder - a phase IV clinical study of FDA data

Summary:

Liver disorder is reported as a side effect among people who take Ozempic (semaglutide), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Metformin, and have Diabetes.

The phase IV clinical study analyzes which people have Liver disorder when taking Ozempic. It is created by eHealthMe based on reports of 28,954 people who have side effects when taking Ozempic from the FDA, and is updated regularly.

What is Ozempic?

Ozempic has active ingredients of semaglutide. It is often used in weight loss. eHealthMe is studying from 29,761 Ozempic users. Check the latest studies of Ozempic.

What is Liver disorder?

Liver disorder (liver diseases) is found to be associated with 1,729 drugs and 2,042 conditions by eHealthMe. Check the latest studies of Liver disorder.



On Jul, 08, 2026

28,954 people reported to have side effects when taking Ozempic.
Among them, 46 people (0.16%) have Liver disorder.

Could Ozempic cause Liver disorder?

Among these 46 people:

How long have people been on Ozempic when they have Liver disorder? *

  • < 1 month: 33.33 %
  • 1 - 6 months: 33.33 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 33.33 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Liver disorder when taking Ozempic? *

  • female: 73.33 %
  • male: 26.67 %

What is the age of people who have Liver disorder when taking Ozempic? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 10.0 %
  • 40-49: 36.67 %
  • 50-59: 16.67 %
  • 60+: 36.67 %

What are other drugs people take besides Ozempic? *

  1. Metformin: 11 people, 23.91%
  2. Prednisolone: 8 people, 17.39%
  3. Folic Acid: 8 people, 17.39%
  4. Magnesium: 7 people, 15.22%
  5. Advair Hfa: 7 people, 15.22%
  6. Potassium Chloride: 7 people, 15.22%
  7. Omeprazole: 7 people, 15.22%
  8. Doxycycline: 7 people, 15.22%
  9. Prednisone: 7 people, 15.22%
  10. Sodium Chloride: 6 people, 13.04%

What are other side effects people have besides Liver disorder? *

  1. Hepatomegaly (abnormal enlargement of the liver): 11 people, 23.91%
  2. Nausea (feeling of having an urge to vomit): 10 people, 21.74%
  3. Fever: 10 people, 21.74%
  4. Headache (pain in head): 9 people, 19.57%
  5. Renal Disorder (kidney disease): 9 people, 19.57%
  6. Weight Decreased: 8 people, 17.39%
  7. Dyspnea (difficult or laboured breathing): 8 people, 17.39%
  8. Lung Disorder (lung disease): 7 people, 15.22%
  9. Diabetes: 7 people, 15.22%
  10. Tumor: 7 people, 15.22%

What are the existing conditions these people have? *

  1. Diabetes: 11 people, 23.91%
  2. Type 2 Diabetes: 9 people, 19.57%
  3. Immunodeficiency Common Variable: 6 people, 13.04%
  4. Fever: 6 people, 13.04%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 8.70%
  6. Nausea (feeling of having an urge to vomit): 4 people, 8.70%
  7. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 6.52%
  8. Psoriasis (immune-mediated disease that affects the skin): 3 people, 6.52%
  9. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 2 people, 4.35%
  10. Diabetic Foot: 2 people, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Ozempic and have Liver disorder?

- Check whether Liver disorder is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ozempic:

Liver disorder treatments and more:

How severe was Liver disorder and when was it recovered:

Expand to all the drugs that have ingredients of semaglutide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ozempic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Liver disorder:

Browse all the conditions that are associated with Liver disorder:


How the study uses the data?

The study uses data from the FDA. It is based on semaglutide (the active ingredients of Ozempic) and Ozempic (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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