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Pacerone and Hyperkalemia - a phase IV clinical study of FDA data

Summary:

Hyperkalemia is reported as a side effect among people who take Pacerone (amiodarone hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Digoxin, and have Cardiac failure congestive.

The phase IV clinical study analyzes which people have Hyperkalemia when taking Pacerone. It is created by eHealthMe based on reports of 2,705 people who have side effects when taking Pacerone from the FDA, and is updated regularly.

What is Pacerone?

Pacerone has active ingredients of amiodarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 2,814 Pacerone users. Check the latest studies of Pacerone.

What is Hyperkalemia?

Hyperkalemia (damage to or disease of the kidney) is found to be associated with 1,956 drugs and 2,937 conditions by eHealthMe. Check the latest studies of Hyperkalemia.

On Jul, 19, 2026

2,705 people reported to have side effects when taking Pacerone.
Among them, 53 people (1.96%) have Hyperkalemia.

Could Pacerone cause Hyperkalemia?

Among these 53 people:

How long have people been on Pacerone when they have Hyperkalemia? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 100 %
  • 10+ years: 0.0 %

What is the gender of people who have Hyperkalemia when taking Pacerone? *

  • female: 50.94 %
  • male: 49.06 %

What is the age of people who have Hyperkalemia when taking Pacerone? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 2.04 %
  • 40-49: 4.08 %
  • 50-59: 22.45 %
  • 60+: 71.43 %

What are other drugs people take besides Pacerone? *

  1. Digoxin: 28 people, 52.83%
  2. Lasix: 23 people, 43.40%
  3. Aspirin: 19 people, 35.85%
  4. Coumadin: 18 people, 33.96%
  5. Coreg: 18 people, 33.96%
  6. Nitroglycerin: 17 people, 32.08%
  7. Furosemide: 17 people, 32.08%
  8. Plavix: 17 people, 32.08%
  9. Protonix: 15 people, 28.30%
  10. Lisinopril: 14 people, 26.42%

What are other side effects people have besides Hyperkalemia? *

  1. Hypotension (abnormally low blood pressure): 22 people, 41.51%
  2. Acute Kidney Failure: 21 people, 39.62%
  3. Cardiac Failure Congestive: 19 people, 35.85%
  4. Chest Pain: 17 people, 32.08%
  5. Weakness: 16 people, 30.19%
  6. Dyspnea (difficult or laboured breathing): 16 people, 30.19%
  7. Anaemia (lack of blood): 15 people, 28.30%
  8. Multiple Injuries: 14 people, 26.42%
  9. Pain: 14 people, 26.42%
  10. Fatigue (feeling of tiredness): 14 people, 26.42%

What are the existing conditions these people have? *

  1. Cardiac Disorder: 4 people, 7.55%
  2. Cardiac Failure Congestive: 4 people, 7.55%
  3. Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 5.66%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 5.66%
  5. Pain: 3 people, 5.66%
  6. High Blood Pressure: 3 people, 5.66%
  7. Malignant Melanoma Site/stage Unspecified (cancer of skin un specific stage): 3 people, 5.66%
  8. Ventricular Fibrillation (abnormally irregular heart rhythm): 2 people, 3.77%
  9. Constipation: 2 people, 3.77%
  10. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 3.77%

* Approximation only. Some reports may have incomplete information.

Do you take Pacerone and have Hyperkalemia?

- Check whether Hyperkalemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pacerone:

Hyperkalemia treatments and more:

How severe was Hyperkalemia and when was it recovered:

Expand to all the drugs that have ingredients of amiodarone hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Pacerone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperkalemia:

Browse all the conditions that are associated with Hyperkalemia:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on amiodarone hydrochloride (the active ingredients of Pacerone) and Pacerone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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