Palbociclib and Hypothyroidism - a phase IV clinical study of FDA data
Summary:
Hypothyroidism is reported as a side effect among people who take Palbociclib (palbociclib), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Letrozole, and have Breast cancer metastatic.
The phase IV clinical study analyzes which people have Hypothyroidism when taking Palbociclib. It is created by eHealthMe based on reports of 11,617 people who have side effects when taking Palbociclib from the FDA, and is updated regularly.
What is Palbociclib?
Palbociclib has active ingredients of palbociclib. eHealthMe is studying from 11,622 Palbociclib users. Check the latest studies of Palbociclib.
What is Hypothyroidism?
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development) is found to be associated with 1,613 drugs and 2,597 conditions by eHealthMe. Check the latest studies of Hypothyroidism.
11,617 people reported to have side effects when taking Palbociclib.
Among them, 44 people (0.38%) have Hypothyroidism.

Among these 44 people:
How long have people been on Palbociclib when they have Hypothyroidism? *
- < 1 month: 5.88 %
- 1 - 6 months: 11.76 %
- 6 - 12 months: 5.88 %
- 1 - 2 years: 70.59 %
- 2 - 5 years: 5.88 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Hypothyroidism when taking Palbociclib? *
- female: 100 %
- male: 0.0 %
What is the age of people who have Hypothyroidism when taking Palbociclib? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 2.5 %
- 40-49: 2.5 %
- 50-59: 17.5 %
- 60+: 77.5 %
What are other drugs people take besides Palbociclib? *
- Letrozole: 11 people, 25.00%
- Zoledronic Acid: 10 people, 22.73%
- Femara: 9 people, 20.45%
- Xgeva: 4 people, 9.09%
- Fulvestrant: 4 people, 9.09%
- Faslodex: 4 people, 9.09%
- Calcium: 4 people, 9.09%
- Arimidex: 4 people, 9.09%
- Azelaic Acid: 3 people, 6.82%
- Alendronic Acid: 2 people, 4.55%
What are other side effects people have besides Hypothyroidism? *
- White Blood Cell Count Decreased: 13 people, 29.55%
- Neoplasm Progression (growth of tumour): 13 people, 29.55%
- High Blood Pressure: 8 people, 18.18%
- Malignant Neoplasm Progression (cancer tumour came back): 8 people, 18.18%
- Metastases To Bone (cancer spreads to bone): 7 people, 15.91%
- Metastases To Liver (cancer spreads to liver): 7 people, 15.91%
- Metastases To Lung (cancer spreads to lung): 7 people, 15.91%
- Full Blood Count Abnormal: 6 people, 13.64%
- Aspartate Aminotransferase Increased: 6 people, 13.64%
- Blood Alkaline Phosphatase Increased: 6 people, 13.64%
What are the existing conditions these people have? *
- Breast Cancer Metastatic: 30 people, 68.18%
- Breast Cancer: 5 people, 11.36%
- Lung Cancer - Non-Small Cell (lung cancer): 2 people, 4.55%
- Nausea (feeling of having an urge to vomit): 1 person, 2.27%
- High Blood Pressure: 1 person, 2.27%
- Depressed Mood: 1 person, 2.27%
* Approximation only. Some reports may have incomplete information.
Do you take Palbociclib and have Hypothyroidism?
- Check whether Hypothyroidism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Palbociclib:
- Palbociclib (11,622 reports)
Hypothyroidism treatments and more:
- Hypothyroidism (168,065 reports)
How severe was Hypothyroidism and when was it recovered:
Expand to all the drugs that have ingredients of palbociclib:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Palbociclib:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Hypothyroidism:
- Hypothyroidism (1,613 drugs)
Browse all the conditions that are associated with Hypothyroidism:
- Hypothyroidism (2,597 conditions)
Related publications that referenced our studies
- Ezeji GC, Inoue T, Bahtiyar G, Sacerdote A, "Hallucinations associated with miglitol use in a patient with chronic kidney disease and hypothyroidism", BMJ case reports, 2015 Feb .
- Ezeji GC, Inoue T, Bahtiyar G, Sacerdote A, "Hallucinations associated with miglitol use in a patient with chronic kidney disease and hypothyroidism", BMJ case reports, 2015 Feb .
How the study uses the data?
The study uses data from the FDA. It is based on palbociclib (the active ingredients of Palbociclib) and Palbociclib (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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