Paliperidone and Myoclonus - a phase IV clinical study of FDA data

Summary:

Myoclonus is reported as a side effect among people who take Paliperidone (paliperidone), especially for people who are female, 40-49 old, also take Escitalopram, and have Major depression.

The phase IV clinical study analyzes which people have Myoclonus when taking Paliperidone. It is created by eHealthMe based on reports of 5,118 people who have side effects when taking Paliperidone from the FDA, and is updated regularly.

What is Paliperidone?

Paliperidone has active ingredients of paliperidone. eHealthMe is studying from 5,137 Paliperidone users. Check the latest studies of Paliperidone.

What is Myoclonus?

Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles) is found to be associated with 759 drugs and 1,139 conditions by eHealthMe. Check the latest studies of Myoclonus.



On Jul, 10, 2026

5,118 people reported to have side effects when taking Paliperidone.
Among them, 15 people (0.29%) have Myoclonus.

Could Paliperidone cause Myoclonus?

Among these 15 people:

What is the gender of people who have Myoclonus when taking Paliperidone? *

  • female: 61.54 %
  • male: 38.46 %

What is the age of people who have Myoclonus when taking Paliperidone? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 61.54 %
  • 50-59: 7.69 %
  • 60+: 30.77 %

What are other drugs people take besides Paliperidone? *

  1. Escitalopram: 8 people, 53.33%
  2. Quetiapine Fumarate: 4 people, 26.67%
  3. Midazolam: 2 people, 13.33%
  4. Diazepam: 2 people, 13.33%
  5. Propofol: 1 person, 6.67%
  6. Levetiracetam: 1 person, 6.67%
  7. Latuda: 1 person, 6.67%

What are other side effects people have besides Myoclonus? *

  1. Muscle Rigidity (muscle stiffness): 5 people, 33.33%
  2. Sedation: 5 people, 33.33%
  3. Tremor (trembling or shaking movements in one or more parts of your body): 4 people, 26.67%
  4. Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time): 4 people, 26.67%
  5. Hyperhidrosis (abnormally increased sweating): 4 people, 26.67%
  6. Movement - Uncontrolled Or Slow: 4 people, 26.67%
  7. Akathisia (a movement disorder characterized by a feeling of inner restlessness): 4 people, 26.67%
  8. Clonus (series of involuntary, rhythmic, muscular contractions and relaxations): 3 people, 20.00%
  9. Altered State Of Consciousness (altered state of mind): 3 people, 20.00%
  10. Resting Tremor (an involuntary somewhat rhythmic, muscle contraction and relaxation during resting condition): 3 people, 20.00%

What are the existing conditions these people have? *

  1. Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 6 people, 40.00%
  2. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 3 people, 20.00%
  3. Drug Dependence: 3 people, 20.00%
  4. Tonic Convulsion (the person will quickly lose consciousness and the skeletal muscles will suddenly tense, often causing the extremities to be pulled towards the body or rigidly pushed away from it): 1 person, 6.67%
  5. Suicidal Ideation: 1 person, 6.67%
  6. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1 person, 6.67%
  7. Schizoaffective Disorder (a mental disorder characterized by disordered thought): 1 person, 6.67%
  8. Psychotic Disorder: 1 person, 6.67%
  9. Negative Thoughts: 1 person, 6.67%
  10. Homicidal Ideation (thoughts about human killing another human): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Paliperidone and have Myoclonus?

- Check whether Myoclonus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Paliperidone:

Myoclonus treatments and more:

How severe was Myoclonus and when was it recovered:

Expand to all the drugs that have ingredients of paliperidone:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Paliperidone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Myoclonus:

Browse all the conditions that are associated with Myoclonus:


How the study uses the data?

The study uses data from the FDA. It is based on paliperidone (the active ingredients of Paliperidone) and Paliperidone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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