Palonosetron and Bone marrow failure - a phase IV clinical study of FDA data

Summary:

Bone marrow failure is reported as a side effect among people who take Palonosetron (palonosetron hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Cimetidine, and have Allergies.

The phase IV clinical study analyzes which people have Bone marrow failure when taking Palonosetron. It is created by eHealthMe based on reports of 5,950 people who have side effects when taking Palonosetron from the FDA, and is updated regularly.

What is Palonosetron?

Palonosetron has active ingredients of palonosetron hydrochloride. eHealthMe is studying from 5,962 Palonosetron users. Check the latest studies of Palonosetron.

What is Bone marrow failure?

Bone marrow failure is found to be associated with 1,013 drugs and 1,438 conditions by eHealthMe. Check the latest studies of Bone marrow failure.

On Jul, 20, 2026

5,950 people reported to have side effects when taking Palonosetron.
Among them, 51 people (0.86%) have Bone marrow failure.

Could Palonosetron cause Bone marrow failure?

Among these 51 people:

How long have people been on Palonosetron when they have Bone marrow failure? *

What is the gender of people who have Bone marrow failure when taking Palonosetron? *

female: 56.82 %
male: 43.18 %

What is the age of people who have Bone marrow failure when taking Palonosetron? *

What are other drugs people take besides Palonosetron? *

What are other side effects people have besides Bone marrow failure? *

Thrombocytopenia (decrease of platelets in blood): 10 people, 19.61%
Nausea (feeling of having an urge to vomit): 6 people, 11.76%
Leukopenia (less number of white blood cells in blood): 5 people, 9.80%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 5 people, 9.80%
Glycosylated Haemoglobin Increased: 4 people, 7.84%
White Blood Cell Count Decreased: 4 people, 7.84%
Nausea And Vomiting: 3 people, 5.88%
Hepatic Function Abnormal: 3 people, 5.88%
Lung Infection: 3 people, 5.88%
Malignant Neoplasm Progression (cancer tumour came back): 3 people, 5.88%

What are the existing conditions these people have? *

Allergies: 13 people, 25.49%
Nausea And Vomiting: 12 people, 23.53%
High Blood Pressure: 11 people, 21.57%
Ovarian Cancer (cancer of ovary): 8 people, 15.69%
Urination - Excessive Volume: 7 people, 13.73%
Constipation: 6 people, 11.76%
Infection: 6 people, 11.76%
White Blood Cell Count Increased: 5 people, 9.80%
Local Anaesthesia: 5 people, 9.80%
Anaemia (lack of blood): 5 people, 9.80%

* Approximation only. Some reports may have incomplete information.

Do you take Palonosetron and have Bone marrow failure?

- Check whether Bone marrow failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Palonosetron:

Palonosetron (5,962 reports)

Browse all side effects of Palonosetron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bone marrow failure:

Bone marrow failure (1,013 drugs)

Browse all the conditions that are associated with Bone marrow failure:

Bone marrow failure (1,438 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on palonosetron hydrochloride (the active ingredients of Palonosetron) and Palonosetron (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.