Pamelor and Hypotension - a phase IV clinical study of FDA data

Summary:

Hypotension is reported as a side effect among people who take Pamelor (nortriptyline hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Neurontin, and have Pain.

The phase IV clinical study analyzes which people have Hypotension when taking Pamelor. It is created by eHealthMe based on reports of 3,798 people who have side effects when taking Pamelor from the FDA, and is updated regularly.

What is Pamelor?

Pamelor has active ingredients of nortriptyline hydrochloride. It is often used in migraine. eHealthMe is studying from 4,069 Pamelor users. Check the latest studies of Pamelor.

What is Hypotension?

Hypotension (abnormally low blood pressure) is found to be associated with 3,352 drugs and 4,763 conditions by eHealthMe. Check the latest studies of Hypotension.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

3,798 people reported to have side effects when taking Pamelor.
Among them, 85 people (2.24%) have Hypotension.

Among these 85 people:

How long have people been on Pamelor when they have Hypotension? *

What is the gender of people who have Hypotension when taking Pamelor? *

female: 70.37 %
male: 29.63 %

What is the age of people who have Hypotension when taking Pamelor? *

What are other drugs people take besides Pamelor? *

What are other side effects people have besides Hypotension? *

Chest Pain: 20 people, 23.53%
Weakness: 20 people, 23.53%
Fatigue (feeling of tiredness): 20 people, 23.53%
Dyspnea (difficult or laboured breathing): 17 people, 20.00%
Dizziness: 16 people, 18.82%
Fever: 14 people, 16.47%
Fall: 14 people, 16.47%
Pain: 13 people, 15.29%
High Blood Pressure: 13 people, 15.29%
Sepsis (a severe blood infection that can lead to organ failure and death): 12 people, 14.12%

What are the existing conditions these people have? *

Pain: 14 people, 16.47%
Stress And Anxiety: 8 people, 9.41%
High Blood Pressure: 7 people, 8.24%
Muscle Spasms (muscle contraction): 6 people, 7.06%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 7.06%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 5 people, 5.88%
Sleep Disorder: 4 people, 4.71%
Gastritis (inflammation of stomach): 4 people, 4.71%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 4.71%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 3 people, 3.53%

* Approximation only. Some reports may have incomplete information.

Do you take Pamelor and have Hypotension?

- Check whether Hypotension is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pamelor:

Pamelor (4,069 reports)

Hypotension treatments and more:

Hypotension (329,859 reports)

Browse all side effects of Pamelor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypotension:

Hypotension (3,352 drugs)

Browse all the conditions that are associated with Hypotension:

Hypotension (4,763 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nortriptyline hydrochloride (the active ingredients of Pamelor) and Pamelor (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.