Paracetamol and Amyotrophy - a phase IV clinical study of FDA data

Summary:

Amyotrophy is reported as a side effect among people who take Paracetamol (acetaminophen), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Hydrea, and have Essential thrombocythaemia.

The phase IV clinical study analyzes which people have Amyotrophy when taking Paracetamol. It is created by eHealthMe based on reports of 114,713 people who have side effects when taking Paracetamol from the FDA, and is updated regularly.

What is Paracetamol?

Paracetamol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 115,650 Paracetamol users. Check the latest studies of Paracetamol.

What is Amyotrophy?

Amyotrophy (muscular wasting or atrophy) is found to be associated with 76 drugs and 232 conditions by eHealthMe. Check the latest studies of Amyotrophy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

114,713 people reported to have side effects when taking Paracetamol.
Among them, 26 people (0.02%) have Amyotrophy.

Among these 26 people:

How long have people been on Paracetamol when they have Amyotrophy? *

What is the gender of people who have Amyotrophy when taking Paracetamol? *

female: 8 %
male: 92 %

What is the age of people who have Amyotrophy when taking Paracetamol? *

What are other drugs people take besides Paracetamol? *

What are other side effects people have besides Amyotrophy? *

Capillary Fragility (lack in resistance of capillary): 15 people, 57.69%
Actinic Keratosis (skin disease due to sun exposure): 15 people, 57.69%
Rash Erythematous (redness of the skin): 15 people, 57.69%
Skin Ulcer: 15 people, 57.69%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 9 people, 34.62%
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream): 8 people, 30.77%
Adrenal Insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids): 8 people, 30.77%
Clostridium Difficile Colitis (inflammation of colon by clostridium difficile bacteria infection): 8 people, 30.77%
Cardio-Respiratory Arrest (sudden dysfunction of heart and lungs): 8 people, 30.77%
Pemphigoid (tense blisters on the skin): 8 people, 30.77%

What are the existing conditions these people have? *

Essential Thrombocythaemia (chronic blood cancer): 14 people, 53.85%
General Physical Health Deterioration (weak health status): 13 people, 50.00%
Inflammation: 10 people, 38.46%
Lung Neoplasm Malignant (cancer tumour of lung): 8 people, 30.77%
Itching: 8 people, 30.77%
Type 2 Diabetes: 1 person, 3.85%
Pneumonia Pneumococcal (pneumococcal pneumonia is a common but serious infection and inflammation of the lungs): 1 person, 3.85%
Meningitis Pneumococcal (a bacterial infection of the membranes covering the brain and spinal cord (meninges)): 1 person, 3.85%
High Blood Pressure: 1 person, 3.85%
Essential Tremor: 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Paracetamol and have Amyotrophy?

- Check whether Amyotrophy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Paracetamol:

Paracetamol (115,650 reports)

Amyotrophy treatments and more:

Amyotrophy (552 reports)

Browse all side effects of Paracetamol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Amyotrophy:

Amyotrophy (76 drugs)

Browse all the conditions that are associated with Amyotrophy:

Amyotrophy (232 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen (the active ingredients of Paracetamol) and Paracetamol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.