Paracetamol and Periodontitis - a phase IV clinical study of FDA data

Summary:

Periodontitis is reported as a side effect among people who take Paracetamol (acetaminophen), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Arava, and have Polyarthritis.

The phase IV clinical study analyzes which people have Periodontitis when taking Paracetamol. It is created by eHealthMe based on reports of 114,713 people who have side effects when taking Paracetamol from the FDA, and is updated regularly.

What is Paracetamol?

Paracetamol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 115,650 Paracetamol users. Check the latest studies of Paracetamol.

What is Periodontitis?

Periodontitis (inflammation of the tissue around the teeth) is found to be associated with 641 drugs and 707 conditions by eHealthMe. Check the latest studies of Periodontitis.

On Aug, 09, 2026

114,713 people reported to have side effects when taking Paracetamol.
Among them, 32 people (0.03%) have Periodontitis.

Among these 32 people:

How long have people been on Paracetamol when they have Periodontitis? *

What is the gender of people who have Periodontitis when taking Paracetamol? *

female: 87.1 %
male: 12.9 %

What is the age of people who have Periodontitis when taking Paracetamol? *

What are other drugs people take besides Paracetamol? *

What are other side effects people have besides Periodontitis? *

Pain In Jaw: 20 people, 62.50%
Osteonecrosis Of Jaw (death of bone of jaw): 20 people, 62.50%
Oral Pain: 20 people, 62.50%
Oral Herpes (viral infection of mouth): 19 people, 59.38%
Gingival Ulceration (ulcer on gums): 17 people, 53.12%
Gastroenteritis (inflammation of stomach and intestine): 11 people, 34.38%
Herpes Simplex (herpes simplex is a common viral infection): 11 people, 34.38%
Periodontal Disease (disease that attacks the gum and bone and around the teeth): 9 people, 28.12%
Necrosis (the death of body tissue): 9 people, 28.12%
Nasopharyngitis (inflammation of the nasopharynx): 5 people, 15.62%

What are the existing conditions these people have? *

High Blood Pressure: 18 people, 56.25%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 18 people, 56.25%
Polyarthritis (arthritis which involves 5 or more joints simultaneously): 18 people, 56.25%
Oral Herpes (viral infection of mouth): 15 people, 46.88%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 15.62%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 4 people, 12.50%
Muscle Spasms (muscle contraction): 4 people, 12.50%
Rickets (softening of bones): 4 people, 12.50%
Osteoporosis (bones weak and more likely to break): 3 people, 9.38%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Paracetamol and have Periodontitis?

- Check whether Periodontitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Paracetamol:

Paracetamol (115,650 reports)

Periodontitis treatments and more:

Periodontitis (4,596 reports)

Browse all side effects of Paracetamol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Periodontitis:

Periodontitis (641 drugs)

Browse all the conditions that are associated with Periodontitis:

Periodontitis (707 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen (the active ingredients of Paracetamol) and Paracetamol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.