Paracetamol and Prothrombin level increased - a phase IV clinical study of FDA data

Summary:

Prothrombin level increased is reported as a side effect among people who take Paracetamol (acetaminophen), especially for people who are female, 30-39 old, have been taking the drug for < 1 month also take Xanax, and have Depression.

The phase IV clinical study analyzes which people have Prothrombin level increased when taking Paracetamol. It is created by eHealthMe based on reports of 114,713 people who have side effects when taking Paracetamol from the FDA, and is updated regularly.

What is Paracetamol?

Paracetamol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 115,650 Paracetamol users. Check the latest studies of Paracetamol.

What is Prothrombin level increased?

Prothrombin level increased is found to be associated with 111 drugs and 251 conditions by eHealthMe. Check the latest studies of Prothrombin level increased.

On Aug, 02, 2026

114,713 people reported to have side effects when taking Paracetamol.
Among them, 12 people (0.01%) have Prothrombin level increased.

Could Paracetamol cause Prothrombin level increased?

Among these 12 people:

How long have people been on Paracetamol when they have Prothrombin level increased? *

What is the gender of people who have Prothrombin level increased when taking Paracetamol? *

female: 83.33 %
male: 16.67 %

What is the age of people who have Prothrombin level increased when taking Paracetamol? *

What are other drugs people take besides Paracetamol? *

What are other side effects people have besides Prothrombin level increased? *

Hepatitis (inflammation of the liver): 7 people, 58.33%
Haemoglobin Decreased: 2 people, 16.67%
International Normalised Ratio Increased: 2 people, 16.67%
Abdominal Pain: 2 people, 16.67%
Urinary Tract Infection: 1 person, 8.33%
Red Cell Distribution Width Increased: 1 person, 8.33%
Escherichia Infection (bacterial infection by escherichia coli): 1 person, 8.33%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 8.33%
Enlarged Heart: 1 person, 8.33%
Electrocardiogram Qrs Complex Prolonged: 1 person, 8.33%

What are the existing conditions these people have? *

Urge Incontinence (urinary incontinence): 1 person, 8.33%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 8.33%
Psychotic Disorder: 1 person, 8.33%
Post Herpetic Neuralgia (neuralgia caused by the varicella zoster virus): 1 person, 8.33%
Otitis Media (inflammation of the middle ear): 1 person, 8.33%
High Blood Pressure: 1 person, 8.33%
High Blood Cholesterol: 1 person, 8.33%
Gout (uric acid crystals building up in the body): 1 person, 8.33%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 8.33%
Depression: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Paracetamol and have Prothrombin level increased?

- Check whether Prothrombin level increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Paracetamol:

Paracetamol (115,650 reports)

Browse all side effects of Paracetamol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Prothrombin level increased:

Prothrombin level increased (111 drugs)

Browse all the conditions that are associated with Prothrombin level increased:

Prothrombin level increased (251 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen (the active ingredients of Paracetamol) and Paracetamol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.