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Paraplatin and Hyponatremia - a phase IV clinical study of FDA data

Summary:

Hyponatremia is reported as a side effect among people who take Paraplatin (carboplatin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Taxol, and have Lung neoplasm malignant.

The phase IV clinical study analyzes which people have Hyponatremia when taking Paraplatin. It is created by eHealthMe based on reports of 12,385 people who have side effects when taking Paraplatin from the FDA, and is updated regularly.

What is Paraplatin?

Paraplatin has active ingredients of carboplatin. eHealthMe is studying from 12,392 Paraplatin users. Check the latest studies of Paraplatin.

What is Hyponatremia?

Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration) is found to be associated with 1,940 drugs and 2,275 conditions by eHealthMe. Check the latest studies of Hyponatremia.

On Aug, 13, 2026

12,385 people reported to have side effects when taking Paraplatin.
Among them, 41 people (0.33%) have Hyponatremia.

Could Paraplatin cause Hyponatremia?

Among these 41 people:

How long have people been on Paraplatin when they have Hyponatremia? *

  • < 1 month: 77.78 %
  • 1 - 6 months: 11.11 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 11.11 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hyponatremia when taking Paraplatin? *

  • female: 53.66 %
  • male: 46.34 %

What is the age of people who have Hyponatremia when taking Paraplatin? *

  • 0-1: 0.0 %
  • 2-9: 3.33 %
  • 10-19: 3.33 %
  • 20-29: 0.0 %
  • 30-39: 6.67 %
  • 40-49: 6.67 %
  • 50-59: 3.33 %
  • 60+: 76.67 %

What are other drugs people take besides Paraplatin? *

  1. Taxol: 18 people, 43.90%
  2. Dexamethasone: 4 people, 9.76%
  3. Decadron: 4 people, 9.76%
  4. Ondansetron: 3 people, 7.32%
  5. Oxycontin: 3 people, 7.32%
  6. Maxipime: 3 people, 7.32%
  7. Fungizone: 3 people, 7.32%
  8. Erbitux: 3 people, 7.32%
  9. Dexamethasone Sodium Phosphate: 3 people, 7.32%
  10. Navelbine: 3 people, 7.32%

What are other side effects people have besides Hyponatremia? *

  1. Dehydration (dryness resulting from the removal of water): 12 people, 29.27%
  2. Thrombocytopenia (decrease of platelets in blood): 9 people, 21.95%
  3. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 8 people, 19.51%
  4. Fever: 6 people, 14.63%
  5. Hypokalemia (low potassium): 6 people, 14.63%
  6. Hypoalbuminaemia (levels of albumin in blood serum are abnormally low): 4 people, 9.76%
  7. Swallowing Difficulty: 4 people, 9.76%
  8. Anaemia (lack of blood): 4 people, 9.76%
  9. Pneumonia: 4 people, 9.76%
  10. Malignant Neoplasm Progression (cancer tumour came back): 3 people, 7.32%

What are the existing conditions these people have? *

  1. Lung Neoplasm Malignant (cancer tumour of lung): 5 people, 12.20%
  2. Febrile Neutropenia (fever with reduced white blood cells): 3 people, 7.32%
  3. Salivary Gland Cancer: 2 people, 4.88%
  4. Endometrial Cancer: 2 people, 4.88%
  5. Adverse Event: 2 people, 4.88%
  6. Tumor: 1 person, 2.44%
  7. Stable Angina (a constant chest pain): 1 person, 2.44%
  8. Ovarian Cancer (cancer of ovary): 1 person, 2.44%
  9. Lung Adenocarcinoma Stage Iv (the cancer has spread to other organs of the body, such as the other lung, brain, or liver): 1 person, 2.44%
  10. Hypopharyngeal Cancer: 1 person, 2.44%

* Approximation only. Some reports may have incomplete information.

Do you take Paraplatin and have Hyponatremia?

- Check whether Hyponatremia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Paraplatin:

Hyponatremia treatments and more:

How severe was Hyponatremia and when was it recovered:

Expand to all the drugs that have ingredients of carboplatin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Paraplatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyponatremia:

Browse all the conditions that are associated with Hyponatremia:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on carboplatin (the active ingredients of Paraplatin) and Paraplatin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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