1. Home
  2. Analysis
  3. Paroxetine
  4. Right-ventricular-failure

Paroxetine and Right ventricular failure - a phase IV clinical study of FDA data

Summary:

Right ventricular failure is reported as a side effect among people who take Paroxetine (paroxetine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Paxil, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Right ventricular failure when taking Paroxetine. It is created by eHealthMe based on reports of 63,800 people who have side effects when taking Paroxetine from the FDA, and is updated regularly.

What is Paroxetine?

Paroxetine has active ingredients of paroxetine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 65,088 Paroxetine users. Check the latest studies of Paroxetine.

What is Right ventricular failure?

Right ventricular failure (right half of the heart fails to work) is found to be associated with 590 drugs and 718 conditions by eHealthMe. Check the latest studies of Right ventricular failure.

On Aug, 06, 2026

63,800 people reported to have side effects when taking Paroxetine.
Among them, 62 people (0.1%) have Right ventricular failure.

Could Paroxetine cause Right ventricular failure?

Among these 62 people:

How long have people been on Paroxetine when they have Right ventricular failure? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 100 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Right ventricular failure when taking Paroxetine? *

  • female: 70.97 %
  • male: 29.03 %

What is the age of people who have Right ventricular failure when taking Paroxetine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 8.82 %
  • 50-59: 32.35 %
  • 60+: 58.82 %

What are other drugs people take besides Paroxetine? *

  1. Paxil: 30 people, 48.39%
  2. Folic Acid: 16 people, 25.81%
  3. Opsumit: 14 people, 22.58%
  4. Veletri: 9 people, 14.52%
  5. Zantac: 7 people, 11.29%
  6. Naloxone: 6 people, 9.68%
  7. Morphine: 6 people, 9.68%
  8. Furosemide: 6 people, 9.68%
  9. Diltiazem Hydrochloride: 5 people, 8.06%
  10. Lasix: 5 people, 8.06%

What are other side effects people have besides Right ventricular failure? *

  1. Hypotension (abnormally low blood pressure): 30 people, 48.39%
  2. Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 28 people, 45.16%
  3. Fever: 27 people, 43.55%
  4. Pulmonary Hypertension (increase in blood pressure in the lung artery): 27 people, 43.55%
  5. Tricuspid Valve Incompetence (inefficient heart valve): 26 people, 41.94%
  6. Enlarged Heart: 25 people, 40.32%
  7. Abdominal Distension: 24 people, 38.71%
  8. Drug Exposure During Pregnancy: 24 people, 38.71%
  9. Skin Discoloration - Bluish (bluish colour of skin): 24 people, 38.71%
  10. Nausea And Vomiting: 23 people, 37.10%

What are the existing conditions these people have? *

  1. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 19 people, 30.65%
  2. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 14 people, 22.58%
  3. Depression: 9 people, 14.52%
  4. Lung Cancer - Non-Small Cell (lung cancer): 5 people, 8.06%
  5. Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 4.84%
  6. Wheezing (a high-pitched whistling sound made while you breath): 2 people, 3.23%
  7. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 3.23%
  8. Neuralgia (pain in one or more nerves): 2 people, 3.23%
  9. Dyspnea (difficult or laboured breathing): 2 people, 3.23%
  10. Dizziness: 2 people, 3.23%

* Approximation only. Some reports may have incomplete information.

Do you take Paroxetine and have Right ventricular failure?

- Check whether Right ventricular failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Paroxetine:

Right ventricular failure treatments and more:

How severe was Right ventricular failure and when was it recovered:

Expand to all the drugs that have ingredients of paroxetine hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Paroxetine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Right ventricular failure:

Browse all the conditions that are associated with Right ventricular failure:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on paroxetine hydrochloride (the active ingredients of Paroxetine) and Paroxetine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe:

© 2026 eHealthMe.com. All rights reserved. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.