Paroxetine and Thyroid function test abnormal - a phase IV clinical study of FDA data

Summary:

Thyroid function test abnormal is reported as a side effect among people who take Paroxetine (paroxetine hydrochloride), especially for people who are female, 40-49 old, also take Biotin, and have Depression.

The phase IV clinical study analyzes which people have Thyroid function test abnormal when taking Paroxetine. It is created by eHealthMe based on reports of 63,800 people who have side effects when taking Paroxetine from the FDA, and is updated regularly.

What is Paroxetine?

Paroxetine has active ingredients of paroxetine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 65,079 Paroxetine users. Check the latest studies of Paroxetine.

What is Thyroid function test abnormal?

Thyroid function test abnormal is found to be associated with 1,718 drugs and 1,580 conditions by eHealthMe. Check the latest studies of Thyroid function test abnormal.

On Oct, 13, 2025

63,800 people reported to have side effects when taking Paroxetine.
Among them, 59 people (0.09%) have Thyroid function test abnormal.

Could Paroxetine cause Thyroid function test abnormal?

Among these 59 people:

What is the gender of people who have Thyroid function test abnormal when taking Paroxetine? *

female: 91.07 %
male: 8.93 %

What is the age of people who have Thyroid function test abnormal when taking Paroxetine? *

What are other drugs people take besides Paroxetine? *

What are other side effects people have besides Thyroid function test abnormal? *

Fatigue (feeling of tiredness): 16 people, 27.12%
Weakness: 15 people, 25.42%
Thrombocytopenia (decrease of platelets in blood): 14 people, 23.73%
Weight Increased: 13 people, 22.03%
Pain: 12 people, 20.34%
Drowsiness: 12 people, 20.34%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 11 people, 18.64%
Urination - Painful: 10 people, 16.95%
Leukopenia (less number of white blood cells in blood): 10 people, 16.95%
Memory Loss: 10 people, 16.95%

What are the existing conditions these people have? *

Depression: 25 people, 42.37%
High Blood Pressure: 13 people, 22.03%
Dyslipidaemia (abnormal amount of lipids): 11 people, 18.64%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 11 people, 18.64%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 11 people, 18.64%
Hair Loss: 10 people, 16.95%
Urination - Painful: 10 people, 16.95%
Vaginal Discharge: 10 people, 16.95%
Nosebleed (bleeding from nose): 10 people, 16.95%
Micturition Disorder (disease of passing urine): 10 people, 16.95%

* Approximation only. Some reports may have incomplete information.

Do you take Paroxetine and have Thyroid function test abnormal?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Paroxetine:

Paroxetine (65,079 reports)

Browse all side effects of Paroxetine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Thyroid function test abnormal:

Thyroid function test abnormal (1,718 drugs)

Browse all the conditions that are associated with Thyroid function test abnormal:

Thyroid function test abnormal (1,580 conditions)

Drugs similar to Paroxetine and Thyroid function test abnormal :

Related publications that referenced our studies

Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .
Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .

How the study uses the data?

The study uses data from the FDA. It is based on paroxetine hydrochloride (the active ingredients of Paroxetine) and Paroxetine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.